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三糖糖-腰部高度比率指数和过度活跃的膀之间的关联:根据NHANES 2005-2018

Haiyan Mao¹, Tong Lin¹, Shanshan Huang¹

¹Department of Critical Care Medicine, Ningbo Medical Center Lihuili Hospital, Ningbo, China.

Frontiers in endocrinology

|April 30, 2025

概括

三糖糖-腰高度比率 (TyG-WHtR) 指数与过度活跃膀 (OAB) 的更高风险有关. 这种代谢标志物显示出预测成年人OAB发展的潜力.

科学领域:

代谢健康和泌尿病学
心血管和代谢疾病风险因素心血管和代谢疾病风险因素
公共卫生和流行病学

背景情况:

三糖糖-腰高度比率 (TyG-WHtR) 指数被认为可以预测心血管和代谢疾病.
代谢性疾病是过度活性膀 (OAB) 的确立危险因素.
泰格-WHtR指数与OAB风险之间的关联以前没有被调查过.

研究的目的:

调查TyG-WHtR指数与发展过度活跃膀 (OAB) 的风险之间的关系.
评估TyG-WHtR指数对OAB的预测值.
探索TyG-WHtR对OAB风险的潜在非线性关系和值影响.

主要方法:

利用了来自全国健康和营养检查调查 (NHANES) 的数据,对14,652名成年人进行了调查.
进行了加权多变量逻辑回归,子组分析和相互作用测试.
采用平滑曲线拟合,值效应分析和接收器操作特征 (ROC) 曲线分析.

主要成果:

在TyG-WHtR指数和OAB发生 (OR=1.646,P<0.001) 之间发现了显著的正相关性,在调整后仍然存在 (OR=1.310,P<0.001).
这种关联受性别和年龄的影响,在TyG-WHtR观察到的值效应为3.579.
TyG-WHtR指数显示了OAB的良好预测能力,其AUC为0.647.

结论:

TyG-WHtR指数与OAB发生有显著的关联,可以作为一种新的风险预测指标.
研究结果表明,OAB的早期检测策略具有潜在的实用性.
建议进行进一步的研究,以确认因果关系,并在不同人群中验证这些发现.

关键词:

尼汉斯 (NHANES) 是一个名人.代谢性疾病是代谢性疾病.过度活动的膀这是一项回顾性研究.三甘油的葡萄糖和腰部高度的比率.

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