全球分子患病率的芭托内拉spp. 在猫和狗:系统性审查和元分析
Aya Attia Koraney Zarea1,2, Maria Tempesta1, Amienwanlen Eugene Odigie1,3
1Department of Veterinary Medicine, University of Bari Aldo Moro, Bari, Italy.
Transboundary and emerging diseases
|April 30, 2025
概括
这项研究显示,全球巴顿氏菌的发病率在猫中为15.3%,在狗中为3.6%. 带有外寄生虫的年轻,自由流浪的猫咪显示出更高的巴顿氏菌感染率.
科学领域:
- 兽医医学 兽医医学 兽医医学
- 传染性疾病 传染性疾病
- 流行病学 流行病学
背景情况:
- 巴托内拉菌种是重要的载体传播病原体,影响动物和人类的健康.
- 了解巴托内拉在物中的全球流行和分布对于公共卫生至关重要.
研究的目的:
- 进行一项元分析,评估巴顿氏菌对物健康的全球影响.
- 确定综合流行率估计,并确定猫和狗中巴顿氏菌感染的风险因素.
主要方法:
- 在Web of Science,PubMed和Scopus进行了系统的文献搜索.
- 使用来自131篇同行评审论文的数据进行了随机效应模型元分析.
- 聚合流行率估计和异质性使用Q-统计和I2指数进行评估.
主要成果:
- 全球患病率估计为猫的15.3%,狗的3.6%,在两种情况下均观察到很高的异质性.
- 猫的巴顿氏菌发病率较高与年龄较小,自由漫游的生活方式和外寄生虫感染有关.
- 猫中最常见的物种是Bartonella henselae,而狗被B. vinsonii亚种感染. 伯克霍菲,B.Hensselae,和其他人.
结论:
- 这一元分析提供了一个全面的全球概述 巴托内拉 spp. 在猫和狗中分布.
- 调查结果突出了特定的风险因素和地理模式,这对于制定有针对性的预防和控制策略至关重要.
- 这项研究强调了解决伴侣动物中巴顿氏菌对于动物和人类健康的重要性.
更多相关视频
10:27Methods to Increase the Sensitivity of High Resolution Melting Single Nucleotide Polymorphism Genotyping in Malaria
Published on: November 10, 2015
11.5K
09:37Navigating MARRVEL, a Web-Based Tool that Integrates Human Genomics and Model Organism Genetics Information
Published on: August 15, 2019
9.6K
相关概念视频
Single Nucleotide Polymorphisms-SNPs
13.6K
A single nucleotide polymorphism or SNP is a single nucleotide variation at a specific genomic position in a large population. It is the most prevalent type of sequence variation found in the human genome. Point mutations that occur in more than 1% of the population qualify as SNPs. These are present once every 1000 nucleotides on an average in the human genome. Replacement of a purine with another purine (A/G) or a pyrimidine with another pyrimidine (C/T) is known as a transition. In contrast,...
13.6K
What is Population Genetics?
56.9K
A population is composed of members of the same species that simultaneously live and interact in the same area. When individuals in a population breed, they pass down their genes to their offspring. Many of these genes are polymorphic, meaning that they occur in multiple variants. Such variations of a gene are referred to as alleles. The collective set of all the alleles within a population is known as the gene pool.
56.9K
Genomics
35.2K
Genomics is the science of genomes: it is the study of all the genetic material of an organism. In humans, the genome consists of information carried in 23 pairs of chromosomes in the nucleus, as well as mitochondrial DNA. In genomics, both coding and non-coding DNA is sequenced and analyzed. Genomics allows a better understanding of all living things, their evolution, and their diversity. It has a myriad of uses: for example, to build phylogenetic trees, to improve productivity and...
35.2K
Genome-wide Association Studies-GWAS
12.0K
Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
GWAS does not require the identification of the target gene involved in...
GWAS does not require the identification of the target gene involved in...
12.0K
Gene Evolution - Fast or Slow?
7.0K
The genomes of eukaryotes are punctuated by long stretches of sequence which do not code for proteins or RNAs. Although some of these regions do contain crucial regulatory sequences, the vast majority of this DNA serves no known function. Typically, these regions of the genome are the ones in which the fastest change, in evolutionary terms, is observed, because there is typically little to no selection pressure acting on these regions to preserve their sequences.
In contrast, regions which code...
In contrast, regions which code...
7.0K
Genomic DNA in Prokaryotes
43.0K
The genome of most prokaryotic organisms consists of double-stranded DNA organized into one circular chromosome in a region of cytoplasm called the nucleoid. The chromosome is tightly wound, or supercoiled, for efficient storage. Prokaryotes also contain other circular pieces of DNA called plasmids. These plasmids are smaller than the chromosome and often carry genes that confer adaptive functions, such as antibiotic resistance.
Genomic Diversity in Bacteria
Although bacterial genomes are much...
Genomic Diversity in Bacteria
Although bacterial genomes are much...
43.0K
