传染途径和一种新的淡水甲动物宿主感染性早发性病毒 (IPV)
Wenyan Xu1, Caiyuan Zhao1, Xiaoyi Pan2
1College of Animal Science and Technology, Henan University of Animal Husbandry and Economy, Zhengzhou, Henan 450046, China.
Transboundary and emerging diseases
|April 30, 2025
概括
在巨型淡水 (Macrobrachium rosenbergii) 中的传染性早发性病毒病 (IPVD) 在经济上是破坏性的. 研究人员确定了淡水甲类动物Macrobrachium nipponense作为传染性早发性病毒 (IPV) 的新宿主,有助于疾病管理.
科学领域:
- 水产养殖病理学 水产养殖病理学
- 传染病流行病学 传染病流行病学
- 类病毒学 类病毒学
背景情况:
- 全球水产养殖至关重要,但传染性早发性病毒病 (IPVD) 在中国造成了重大经济损失.
- 由传染性早熟病毒 (IPV) 引起的IPVD导致感染的的性早熟和发育迟缓.
- 了解IPV传播途径和宿主范围对于有效的疾病预防和控制策略至关重要.
研究的目的:
- 为了调查IPV在Macrobrachium rosenbergii中的传播途径.
- 为了确定IPV的宿主范围.
- 为了确定IPV的新宿主,并评估它们的易感性和病理影响.
主要方法:
- 传播实验包括摄入受感染的组织,病毒过物浸泡,同居和水传播暴露.
- 在各种鱼类和物种以及Macrobrachium nipponense.se.上进行了人工感染试验.
- 嵌套PCR被用于检测两年内从Macrobrachium nipponense收集的样本中的IPV存在.
主要成果:
- 在Macrobrachium rosenbergii中没有观察到IPV的垂直传播,从蛋到成年阶段.
- 马克罗布拉希乌尼波尼尼斯被证实是IPV的新甲宿主,在特定的组织 (脚动物,大脑,眼睛,) 中表现出缓慢的生长和IPV存在.
- 鱼类 (Carassius auratus,Pangasius bocourti,Micropterus salmoides,Oreochromis mossambicus) 和类 (Scylla paramamosain,Eriocheir sinensis) 的检测结果没有为IPV呈阳性.
结论:
- 通过环境暴露和直接接触,IPV的传播是水平的,而不是垂直的,在Macrobrachium rosenbergii.
- 麦克罗布拉基乌尼波尼尼斯 (Macrobrachium nipponense) 作为IPV的新型水库,可能会影响混合物种水产养殖.
- 这些发现为开发类水产养殖中的有针对性的IPV管理和预防策略提供了关键的见解.
相关概念视频
Retrovirus Life Cycles
45.3K
Retroviruses have a single-stranded RNA genome that undergoes a special form of replication. Once the retrovirus has entered the host cell, an enzyme called reverse transcriptase synthesizes double-stranded DNA from the retroviral RNA genome. This DNA copy of the genome is then integrated into the host’s genome inside the nucleus via an enzyme called integrase. Consequently, the retroviral genome is transcribed into RNA whenever the host’s genome is transcribed, allowing the...
45.3K
Infection
6.4K
When a pathogen enters the body and reproduces, it can cause an infection, damage body cells, and cause illness symptoms that eventually lead to disease. Therefore, its prevention requires breaking the chain of infection.
The chain begins with pathogens: bacteria, viruses, fungi, prions, or parasites such as protozoa helminths. These can be present on the skin as transient or resident flora, or they can be acquired from the environment. Identifying and treating the type of infection and...
The chain begins with pathogens: bacteria, viruses, fungi, prions, or parasites such as protozoa helminths. These can be present on the skin as transient or resident flora, or they can be acquired from the environment. Identifying and treating the type of infection and...
6.4K
Viral Recombination
23.1K
Cells are sometimes infected by more than one virus at once. When two viruses disassemble to expose their genomes for replication in the same cell, similar regions of their genomes can pair together and exchange sequences in a process called recombination. Alternatively, viruses with segmented genomes can swap segments in a process called reassortment.
23.1K
Retroviruses
12.1K
Retroviruses and retrotransposons both insert copies of their genetic elements into the genome of the host cell. Thus, the viral genes are passed on when the host genome is replicated or translated. A typical retroviral DNA sequence contains 3-4 genes that encode the different proteins required for its structural assembly and function as a molecular parasite. This DNA is transcribed into a single mRNA, which is very similar in structure to conventional mRNAs, i.e., it is capped at the 5’...
12.1K
Intracellular Movement of Viruses and Bacteria
2.7K
Intracellular bacteria and viruses often comprise a group of highly infectious pathogens that can cause several diseases. Bacterial pathogens include those belonging to the genus Rickettsia responsible for conditions such as rocky mountain spotted fever and the Mediterranean spotted fever; Chlamydia, a genus responsible for a sexually transmitted disease; Coxiella burnetii, an agent responsible for Q fever. Viral pathogens include vaccinia—a poxvirus, and herpes simplex virus—a...
2.7K


