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Updated: May 9, 2025

Sequence-specific and Selective Recognition of Double-stranded RNAs over Single-stranded RNAs by Chemically Modified Peptide Nucleic Acids
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识别针对胰岛素受体异型A的向抑制的反感性寡核酸

Christopher A Galifi1, Ryan J Dikdan2, Divyangi Kantak1

  • 1Department of Pharmacology, Physiology, & Neuroscience, Center for Cell Signaling and Cancer Institute of New Jersey, Rutgers Biomedical and Health Sciences, Newark, NJ, United States.

Frontiers in oncology
|April 30, 2025
PubMed
概括

研究人员开发了一种反感性寡核酸 (ASO),可以选择性地向与癌症相关的胰岛素受体异型A (IR-A). 这种新型的ASO有效地减少了各种癌细胞中的IR-A表达,提供了潜在的治疗应用.

关键词:
这就是IR-A.反感的寡核化物.乳腺癌 乳腺癌 乳腺癌癌症治疗方法 癌症治疗方法胰岛素受体的胰岛素受体

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