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对结直肠腺瘤进行水下和常规冷陷多眼术进行比较:前性随机对照试验

Biao Fu¹, Xiangrong Zhou¹, Tian Xiaofeng²

¹Department of Gastroenterology, Jianyang People's Hospital, Jianyang, Chengdu, China.

Endoscopy international open

|April 30, 2025

概括

水下冷陷多角切除术 (UCSP) 与标准冷陷多角切除术 (CSP) 相比,对于结直肠腺瘤提供更高的完整切除率. 这种技术对于尺寸为4至9毫米的息肉是安全有效的.

科学领域:

胃肠病学胃肠病学
内視鏡外科手術內視鏡外科手術
结肠直肠癌预防预防

背景情况:

结肠直肠腺瘤是癌前病变,需要完全切除.
传统的冷陷多角切除术 (CSP) 是一种常见的腺瘤切除方法.
评估用于改善腺瘤切除的新技术对于预防结直肠癌至关重要.

研究的目的:

为了比较水下冷陷多角切除术 (UCSP) 与常规冷陷多角切除术 (CSP) 的疗效和安全性.
评估结直肠腺瘤的完整切除率 (R0) 和肌肉粘膜切除率.
评估UCSP的安全概况,包括操作时间和不良事件.

主要方法:

进行了一项单中心,前性,随机对照试验.
患有4-9毫米结直肠腺瘤的患者被随机分配到UCSP或CSP.
使用窄带成像,并通过活检评估切除完整性.

主要成果:

水下冷陷多角切除术 (UCSP) 与CSP (86.7%) 相比,显著提高了R0切除率 (96.7%).
肌肉粘膜切除率在UCSP (68.9%) 与CSP (43.8%) 相比也显著更高.
手术时间相似,在分组之间没有观察到延迟出血或穿孔的显著差异.

结论:

水下冷陷多角切除术 (UCSP) 在大小为4-9毫米的结直肠腺瘤中实现了高R0切除率.
UCSP是一种安全有效的内镜技术,用于结直肠腺瘤治疗.
这项研究支持UCSP作为实现完全腺瘤切除的优越方法.

关键词:

内镜切除 (多眼切除,ESD,EMRc,等等) 的方法内镜下部消化道下部消化道多胞胎 / 腺瘤 / ...组织诊断组织诊断

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