一般人群对周围血液染色体测试在婚前或怀孕前的背景中的知识,态度和实践
Caixia Hu1, Lulu Zhai1, Hailian Wang1
1Hangzhou Linping District Maternal & Child Health Care Hospital, Hangzhou, China.
Molecular genetics & genomic medicine
|April 30, 2025
概括
一般人群对婚前血液染色体检测的知识较低,但态度和做法积极. 提高知识和态度可以提高测试吸收率.
科学领域:
- 生殖健康 生殖健康
- 基因检测 基因检测 基因检测
- 公共卫生 公共卫生
背景情况:
- 之前的研究重点是产前遗传测试,而不是婚前/孕前染色体测试.
- 关于婚前/怀孕前血液染色体检测的公众知识,态度和实践 (KAP) 的数据有限.
研究的目的:
- 调查关于外周血液染色体检测的一般人群的KAP.
- 为了确定影响KAP的因素,进行婚前或怀孕前的染色体检测.
主要方法:
- 从10月到2023年12月进行了一项横截面研究.
- 630名接受免费婚前或怀孕前检查的个人填写了自己设计的问卷.
- 数据分析包括曼-惠特尼U,克鲁斯卡尔-瓦利斯H,皮尔森相关性和多变量后勤回归.
主要成果:
- 平均KAP分数为63.00%的知识,81.98%的态度,83.69%的实践.
- 女性表现出比男性更高的态度和练习得分.
- 知识和态度得分与实践得分独立相关.
结论:
- 杭州的普通人口对婚前/怀孕前血液染色体检测的知识很少,但态度和做法很好.
- 提高公众的知识和积极态度对于改善测试实践至关重要.
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