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Updated: Jul 9, 2026

High-resolution Melting PCR for Complement Receptor 1 Length Polymorphism Genotyping: An Innovative Tool for Alzheimer's Disease Gene Susceptibility Assessment
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高分辨率测序确定了六个新的HLA-DRB1等位基因

Maria Loginova1,2, Daria Smirnova1, Igor Paramonov1

  • 1Federal State Budget Research Institution: Kirov Hematology and Blood Transfusion Research Institute Under the Federal Medicine and Biology Agency, Kirov, Russia.

HLA
|April 30, 2025
PubMed
概括

在骨髓捐赠者身上发现了6种新的人类白细胞抗原 (HLA) -DRB1等位基因. 这些发现扩大了俄罗斯人口中已知的HLA-DRB1遗传多样性.

关键词:
在HLA-DRB1中.没有NGS,没有NGS.骨髓捐赠者提供了骨髓.一个新型的等位基因

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相关概念视频

Genome-wide Association Studies-GWAS01:11

Genome-wide Association Studies-GWAS

Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
GWAS does not require the identification of the target gene involved in...