低收入国家的儿科疼痛和营养不良:叙事性审查
1Musculoskeletal Research Unit, Department of Rehabilitation Sciences, Faculty of Movement and Rehabilitation Sciences, Leuven University, Leuven, Belgium.
Nutrition and health
|April 30, 2025
概括
儿童营养不良可能导致全身慢性炎症 (SCI) 并改变大脑发育,可能导致长期疼痛. 需要一个整体的方法来解决这个复杂的问题.
科学领域:
- 儿科健康 儿科健康
- 营养科学 营养科学
- 疼痛研究 疼痛研究
背景情况:
- 儿科疼痛很普遍,但人们对其了解甚少,特别是在低收入环境中.
- 系统性慢性炎症 (SCI) 可能是持续疼痛的基础,并与营养不良有关.
- 了解这种联系对于有效的儿童疼痛管理至关重要.
研究的目的:
- 研究儿童疼痛与低收入国家营养不良之间的潜在关联.
- 探索与营养不良,SCI和儿童疼痛感知有关的机制.
主要方法:
- 进行了文学叙事审查.
- 在PubMed,EMBASE,Web of Science和Scopus数据库中进行了全面的搜索.
- 使用的关键词与营养不良,疼痛,SCI和儿科人口相关.
主要成果:
- 营养不良会影响知觉大脑的发育,并改变整个生命的疼痛感知.
- 中度急性营养不良可以诱导慢性炎症和超炎症反应.
- 系统性炎症与广泛的肌肉骨疼痛敏感性有关.
结论:
- 营养不良可能有助于发展可感性大脑和SCI,使儿童易患慢性疼痛.
- 目前对儿科疼痛的生物物理方法可能需要修订.
- 建议采用多维,跨学科的方法,包括营养和微生物组干预措施.
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