Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Safety and Operative Outcomes of the Use of Resorbable Distractors in Posterior Cranial Vault and Mandibular Distraction.

The Journal of craniofacial surgery·2026
Same author

Electrospun Polycaprolactone/Collagen Scaffolds Enhance Manipulability and Influence the Composition of Self-Assembled Extracellular Matrix.

Bioengineering (Basel, Switzerland)·2025
Same author

Correction of Significant Urethral Anomalies Using a Tissue-Engineered Human Urethral Substitute: Proof of Concept.

International journal of molecular sciences·2025
Same author

Adaptation of a standardized self-reported cost questionnaire specific for the severe burn injury population (BI-CoPaQ).

Burns : journal of the International Society for Burn Injuries·2024
Same author

Improving Cutaneous Wound Healing in Diabetic Mice Using Naturally Derived Tissue-Engineered Biological Dressings Produced under Serum-Free Conditions.

Stem cells international·2024
Same author

The economic burden of burned patients for hospitalization in Canada.

Burns : journal of the International Society for Burn Injuries·2024

相关实验视频

Updated: May 15, 2025

Mechanical Micronization of Lipoaspirates for Regenerative Therapy
05:02

Mechanical Micronization of Lipoaspirates for Regenerative Therapy

Published on: March 15, 2019

7.5K

使用可溶性分子预条件改善脂肪移植的生存率.

Nabil Amraoui1,2, Isabelle Xu2, Jorge Robles Cortés2

  • 1Regenerative Medicine Division, CHU de Quebec-Université Laval Research Center, Quebec, QC G1J 1Z4, Canada.

Biomolecules
|April 30, 2025
PubMed
概括

可溶性分子可以通过支持脂肪细胞的产生,增强血管生长和减少氧化应激来改善脂肪移植结果. 需要进一步的研究来优化它们在临床应用中的使用.

关键词:
脂质生成 (adipogenesis) 是一种脂肪组织的脂肪组织.血管新生的产生.抗氧化剂是一种抗氧化剂.脂肪移植的生存率 脂肪移植的生存率脂肪接种 脂肪接种氧化应激是一种氧化应激.这是一个预先条件.保持体积的体积保留.

更多相关视频

Stromal Vascular Fraction-enriched Fat Grafting for the Treatment of Symptomatic End-neuromata
07:58

Stromal Vascular Fraction-enriched Fat Grafting for the Treatment of Symptomatic End-neuromata

Published on: November 23, 2017

7.6K
Assessment of Viability of Human Fat Injection into Nude Mice with Micro-Computed Tomography
11:13

Assessment of Viability of Human Fat Injection into Nude Mice with Micro-Computed Tomography

Published on: January 7, 2015

11.0K

相关实验视频

Last Updated: May 15, 2025

Mechanical Micronization of Lipoaspirates for Regenerative Therapy
05:02

Mechanical Micronization of Lipoaspirates for Regenerative Therapy

Published on: March 15, 2019

7.5K
Stromal Vascular Fraction-enriched Fat Grafting for the Treatment of Symptomatic End-neuromata
07:58

Stromal Vascular Fraction-enriched Fat Grafting for the Treatment of Symptomatic End-neuromata

Published on: November 23, 2017

7.6K
Assessment of Viability of Human Fat Injection into Nude Mice with Micro-Computed Tomography
11:13

Assessment of Viability of Human Fat Injection into Nude Mice with Micro-Computed Tomography

Published on: January 7, 2015

11.0K

科学领域:

  • 生物医学工程 生物医学工程
  • 再生医学是一种再生医学.
  • 整形外科 整形外科 整形外科

背景情况:

  • 脂肪移植是用于软组织缺陷的常见整形手术技术.
  • 由于脂肪细胞死亡和组织重塑,长期体积保持不佳限制了它的有效性.
  • 优化脂肪移植需要策略来增强移植的生存和整合.

研究的目的:

  • 审查关于可溶性分子的临床前和临床研究,以改善脂肪移植结果.
  • 根据它们在增强脂肪移植保留方面的作用机制来分类分子.
  • 确定这些分子临床翻译的挑战和未来方向.

主要方法:

  • 临床前和临床研究的范围审查.
  • 针对脂肪生成,血管化和氧化应激的分子分析.
  • 讨论18种特定分子,包括胰岛素,VEGF和黑激素.

主要成果:

  • 可溶性分子可以通过三个主要机制改善脂肪移植的保留.
  • 观察到增强脂肪生成,改善血管化和减少氧化应激.
  • 许多生物分子表现出增加细胞存活率和体积保留的潜力.

结论:

  • 生物分子有望改善长期脂肪移植结果.
  • 实验方案的变化和有限的临床数据阻碍了翻译.
  • 未来的研究应该集中在剂量,输送和标准化临床试验上,以获得最佳的预先条件.