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单细胞转录基因分析揭示了血液组织中人类iNKT细胞的多样性

Reyka G Jayasinghe1, Derek Hollingsworth2, Nathan C Schedler3

  • 1Department of Medicine, Division of Oncology, Washington University School of Medicine, Saint Louis, MO, USA.

Cell reports
|April 30, 2025
PubMed
概括

人类不变天然杀手T (iNKT) 细胞表现出多样化的转录组特征,包括天真/前体和T助手类子集,为细胞疗法提供了洞察力. 这项研究揭示了新的转录因子动态和CD8+iNKT细胞模式.

关键词:
CP: 细胞生物学 细胞生物学CP: 免疫学 免疫学在T效应器内存 RA RA中.这就是TEMRA.这种差异化的差异化.细胞疗法是细胞疗法.接种与宿主病的疾病.在iNKT细胞中.原始的淋巴细胞是先天性淋巴细胞.不变的自然杀手T细胞淋巴细胞的发展.淋巴细胞子集 淋巴细胞子集

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