在患者护理区域对抗新生菌药物污染的表面擦拭采样进行范围审查
AnnMarie L Walton1, Melissa A Powell1, Leila Ledbetter2
1Duke University School of Nursing, Durham, North Carolina.
Journal of occupational and environmental hygiene
|April 30, 2025
概括
医疗保健工作者面临抗瘤药物 (AD) 暴露的风险. 这些危险药物 (HDs) 的表面污染在患者区域很常见,需要标准化的监测和保护措施.
科学领域:
- 职业健康 职业健康 职业健康
- 环境污染 环境污染
- 制药科学 制药科学
背景情况:
- 医疗保健工作者面临着因抗瘤药物 (AD) 暴露而对健康产生不利影响的风险.
- 尽管目前的干预措施,但表面的ADS污染仍然存在.
- 现有的指导方针缺乏针对暴露控制的AD,表面和采样区域的具体性.
研究的目的:
- 为了识别患者护理区域中被ADs污染的特定表面.
- 审查评估的防范剂量,污染百分比,采样区域和保护措施的使用.
- 为了为AD表面污染数据收集的标准化提供信息.
主要方法:
- 对2004年1月1日以后出版的文献进行综述.
- 分析评估ADs,表面污染,采样区域和个人防护设备 (PPE) 或封闭系统传输设备 (CSTD) 的研究.
- 识别常用的分析方法 (GC-MSMS,LC-MSMS) 和受污染的表面.
主要成果:
- 环胺是最频繁采样的AD.
- 通常受污染的表面包括地板,柜台,输液杆,病人桌子和门把手.
- 大多数研究采样了100900平方厘米的面积,通常是在工作日结束时.
- 个人防护设备和CSTD的使用报告不一致.
结论:
- 环境污染与ADs在医疗保健机构的各种表面普遍存在.
- 关于PPE和CSTD使用的标准化数据收集至关重要.
- 改善报告可以帮助减轻医疗保健工作者接触危险药物的风险.
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