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Viral Tracing of Genetically Defined Neural Circuitry
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病毒诱导的RGMa表达驱动HTLV-1相关骨髓病变中的神经退行

Natsumi Araya1, Makoto Yamagishi2, Makoto Nakashima1

  • 1Department of Rare Diseases Research, St. Marianna University School of Medicine, Kanagawa, Japan.

JCI insight
|April 30, 2025
PubMed
概括

人类T淋巴细胞病毒1型关联骨髓病变 (HAM) 涉及由RGMa介导的神经元损伤. 一种中和抗体ununasnemab有效地减少了这种损伤,表明RGMa是HAM的潜在治疗标.

关键词:
传染病 传染病 传染病 传染病神经退行发生神经退行.神经科学是一个神经科学.在T细胞,T细胞.转录 转录 转录 转录

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