大脑网络的功能连接和皮层激活功能在吞任务期间,用于中风后的患者:多道的皮研究:多道的皮研究
11Department of Rehabilitation Medicine, Affiliated Hospital of North Sichuan Medical College, Nanchong, Sichuan, China.
Georgian medical news
|April 30, 2025
概括
与健康人相比,中风后消化不良 (PSD) 患者在吞任务期间表现出大脑网络功能连接的减少. 这种减少的连接性与吞的严重性相关,并可能预测需要输液管养.
科学领域:
- 神经科学是一个神经科学.
- 医疗成像医学成像
- 康复科学 康复科学 康复科学
背景情况:
- 脑卒中后消化不良症 (PSD) 在吞功能方面存在挑战.
- 功能近红外光谱 (fNIRS) 是一种新兴的非侵入性脑成像技术.
- fNIRS为PSD患者的功能性大脑连接提供了新的见解.
研究的目的:
- 使用fNIRS. 在吞任务期间,比较健康对照组 (HC) 和PSD患者之间的大脑网络功能连接和激活.
- 调查PSD背后的机制.
- 为了确定PSD治疗的潜在神经调节点.
主要方法:
- 招募了26名HC和53名PSD患者 (分为出血和缺血子组).
- 使用fNIRS在吞任务期间收集数据.
- 分析了与吞相关的感兴趣区域 (ROI) 的功能连接强度和大脑激活.
- 与临床指标进行了相关性和ROC曲线分析.
主要成果:
- 与HC相比,PSD患者在吞相关区域的脑网络功能连接强度显著降低 (p<0.05).
- 在PSD出血和缺血子组之间没有发现连接性的显著差异.
- 与吞相关的皮质功能连接强度与PSD患者的吞功能严重程度相关.
- 功能连接可以作为预测管道养依赖性的指标.
结论:
- 在吞过程中,PSD患者表现出功能连接性减弱和脑网络激活异常.
- 这些发现为PSD的潜在机制提供了证据.
- 确定了PSD治疗干预的潜在神经调节标.
更多相关视频
06:18Qualitative and Comparative Cortical Activity Data Analyses from a Functional Near-Infrared Spectroscopy Experiment Applying Block Design
Published on: December 3, 2020
3.6K
09:42Author Spotlight: Using Motor Imagery Brain-Computer Interface to Improve Motor and Cognitive Function in Stroke Patients
Published on: September 1, 2023
1.1K
相关概念视频
Long-term Potentiation
Long-term potentiation, or LTP, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTP is the process of synaptic strengthening that occurs over time between pre- and postsynaptic neuronal connections. The synaptic strengthening of LTP works in opposition to the synaptic weakening of long-term depression (LTD) and together are the main mechanisms that underlie learning and memory.
Long-term Potentiation
Long-term potentiation, or LTP, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTP is the process of synaptic strengthening that occurs over time between pre and postsynaptic neuronal connections. The synaptic strengthening of LTP works in opposition to the synaptic weakening of long-term depression (LTD) and together are the main mechanisms that underlie learning and memory.
Hebbian LTP
LTP can occur when presynaptic neurons...
Hebbian LTP
LTP can occur when presynaptic neurons...
Brainstem
The brainstem, located inferior to the brain and superior to the spinal cord, serves as a bridge between the cerebrum and the spinal cord. It plays a vital role in relaying information and controlling critical life functions. It comprises three primary regions: the midbrain, pons, and medulla oblongata.
The Midbrain
The midbrain is located beneath the diencephalon and connects the cerebrum with the lower parts of the brain. The cerebral peduncles are prominent midbrain structures that house the...
The Midbrain
The midbrain is located beneath the diencephalon and connects the cerebrum with the lower parts of the brain. The cerebral peduncles are prominent midbrain structures that house the...
Functional Brain Systems: Limbic System
The limbic system, often called the "emotional brain," is a complex set of structures located deep within the brain. The intricate network of the limbic system supports a wide range of psychological functions, from emotional regulation to memory formation and sensory processing. This functional brain region encompasses specific parts of the diencephalon and the cerebrum, integrating the higher mental functions of the cerebral cortex with the primitive emotional responses of the deep brain...
Functional Brain Systems: Reticular Formation
The reticular formation is a complex network of gray and white matter located within the brainstem extending from the medulla to the midbrain.
Within the reticular formation, there are several distinct nuclei that can be classified into three broad categories. The Raphe nuclei are located along the midline of the brainstem. They are primarily known for their role in synthesizing and releasing serotonin, a neurotransmitter involved in regulating mood, appetite, sleep, and circadian rhythms. The...
Within the reticular formation, there are several distinct nuclei that can be classified into three broad categories. The Raphe nuclei are located along the midline of the brainstem. They are primarily known for their role in synthesizing and releasing serotonin, a neurotransmitter involved in regulating mood, appetite, sleep, and circadian rhythms. The...
Neuroplasticity
Neuroplasticity reflects the brain's remarkable capacity to adapt and evolve, responding dynamically to learning, experiences, or injury by reorganizing its neural circuitry. This reorganization involves creating new neural connections and refining old ones through a series of biological processes that contribute to the brain's lifelong development and adaptability.
