膜保护的多模板分子印制聚合物基微固相提取与高性能液态色谱相结合,用于分析二
Xiuqi Lang1, Shanchao Fu1, Huizhen Zhao1
1Faculty of Light Industry, Qilu University of Technology (Shandong Academy of Sciences), Jinan 250353, PR China.
Journal of chromatography. A
|April 30, 2025
概括
一种新方法使用多模板分子印记材料 (mt-MIPs) 在微固体相提取 (μ-SPE) 装置中,用于快速和选择性 (CP) 分析皮革. 这种技术为复杂矩阵中检测CP提供了高灵敏度和精度.
科学领域:
- 分析化学 分析化学
- 材料科学 材料科学 材料科学
- 环境科学 环境科学
背景情况:
- 类 (CPs) 是皮革加工中常见的污染物,具有环境和健康风险.
- 由于矩阵效应和低度,在像皮革这样的复杂矩阵中准确确定CP是具有挑战性的.
研究的目的:
- 开发一种敏感和选择性的方法,用于同时提取和确定皮革矩阵中的五种典型CP.
- 创建一个微固态相提取 (μ-SPE) 装置,使用多模板分子打印材料 (mt-MIPs) 进行高效的CP分析.
主要方法:
- 使用半孔改性多壁碳纳米管 (MWCNTs@mSi) 作为支材料制备mt-MIP.
- 通过将mt-MIP密封到多孔尼龙膜中制造μ-SPE设备.
- 优化μ-SPE参数,并与高性能液体染色学 (HPLC) 进行合,用于CP分析.
主要成果:
- mt-MIPs表现出高吸附能力 (39.1571.43毫克g-1) 和快速的质量转移 (在30分钟内).
- 开发的mt-MIPs-μ-SPE-HPLC方法显示出良好的线性 (2.0200 μg L−1),高灵敏度 (LODs 0.170.52 μg L−1),以及高的丰富系数 (70.6144).
- 成功应用于制废水,成品皮革和湿蓝样本,可接受的回收率 (73.00%115.2%) 和低RSD (0.28%11.4%).
结论:
- 开发的mt-MIPs-μ-SPE-HPLC方法是有效的同时提取和量化复杂的皮革矩阵中的微量CP.
- 该方法表现出高选择性,灵敏性和稳定性,使其适合常规分析.
- 这种方法为皮革行业的CP监控提供了可行的解决方案,以确保环境和产品安全.
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