在日本医院使用抗微生物药物:2020年爱知点患病率调查结果
Hiroshi Morioka1, Yusuke Koizumi2, Keisuke Oka3
1Department of Infectious Diseases, Nagoya University Hospital, 466-8560, Nagoya, Aichi, Japan.
The Journal of hospital infection
|April 30, 2025
概括
这项研究调查了日本医院的抗菌剂使用情况,发现近30%的住院患者接受了抗菌剂. 关键发现包括医院规模的使用差异和长期的手术抗微生物预防.
科学领域:
- 传染性疾病 传染性疾病
- 医院 医院 药房 医院药房
- 公共卫生 公共卫生
背景情况:
- 全面的抗微生物药物使用 (AMU) 数据对于有效的抗微生物药物管理至关重要.
- 日本医院内对AMU的定性数据有限.
研究的目的:
- 为日本医院的住院患者提供抗菌药物使用的概述.
- 识别抗微生物药物处方实践中的模式和变化.
主要方法:
- 2020年在日本爱知县进行了一项多中心点患病率调查.
- 收集的数据包括患者人口统计,潜在疾病,AMU指示 (CAI/HAI治疗,SP,MP),治疗感染和AST干预.
- 分析了27家医院的10,199名患者.
主要成果:
- 在10,199名住院患者中,有29.6%的患者被处方抗菌药,总共处方3738份.
- 主要适用于社区感染 (CAI) 治疗 (40.4%),医疗相关感染 (HAI) 治疗 (21.8%),手术预防 (SP) (19.9%) 和医疗预防 (MP) (17.1%).
- 抗微生物药物的使用强度因医院规模而异,在31.2%的病例中观察到长期的SP. 经常处方的是塞法索林,塞夫特里亚克松和三甲-硫甲醇.
结论:
- 这项研究提供了来自日本一个地区的全面AMU数据,揭示了显著的差异.
- 医院规模对抗微生物药物的处方模式产生影响.
- 频繁使用用于HAI的宽谱药物,高的MP率与三甲胺-硫甲醇,并扩展SP保证注意抗菌管理.
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