用青少年和青少年的安全替代方案预防自杀 (SAFETY):一个随机的可行性试验
Moa Karemyr1, Martin Bellander2, Moa Pontén2
1Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden moa.karemyr@ki.se.
BMJ mental health
|April 30, 2025
概括
基于家庭的青少年和青年安全替代方案 (SAFETY) 治疗是可行的,并显示出减少自杀行为和改善青少年心理健康的前景. 需要进一步的研究来证实它在更大的试验中的有效性.
科学领域:
- 精神病学是一个精神病学.
- 儿童和青少年心理健康
- 临床心理学 临床心理学
背景情况:
- 青少年的自杀行为是一个重要的公共卫生问题,有效的治疗选择有限.
- 迫切需要基于证据的干预措施来解决青少年自杀企图的问题.
研究的目的:
- 评估基于家庭的认知行为疗法 (CBT) 计划的可行性和初步有效性,称为青少年和青年安全替代方案 (SAFETY).
- 为了将SAFETY与近期自杀行为青少年的积极对照 (支持性治疗) 进行比较.
主要方法:
- 瑞典的一项随机对照试验,涉及30名青少年 (93%为女性,平均年龄为14.6岁),最近有自杀行为.
- 参与者被分配到12周的SAFETY或支持性治疗,结果在治疗后3个月评估.
- 可行性是通过治疗遵守,满意度,可信度和不良事件来衡量的. 其次结果包括自杀企图,自我伤害,焦虑,抑郁,生活质量和情绪失调.
主要成果:
- 两种治疗方法都显示出高可行性,具有良好的服从性,满意度和低消耗率.
- 在3个月后,14%的SAFETY和27%的支持性治疗有自杀企图. 在这两组中,非自杀性自我伤害显著下降,安全性下降更大 (95%对69%).
- 安全性在焦虑,抑郁,生活质量和情绪失调方面表现出中等至大程度的改善,这些在支持性治疗组中没有观察到.
结论:
- 基于家庭的SAFETY干预似乎是可行的,并且对有自杀倾向的青少年来说是有希望的.
- 建议进行一项较大的随机对照试验,以进一步验证SAFETY计划的有效性.
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