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Updated: May 9, 2025

Induction of Mesenchymal-Epithelial Transitions in Sarcoma Cells
11:42

Induction of Mesenchymal-Epithelial Transitions in Sarcoma Cells

Published on: April 7, 2017

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[结构生物学中的一个显著的进步,旨在阐明突肉瘤发展的机制]

Kenji Iwasaki1,2, Satoshi Takenaka3

  • 1TARA, University of Tsukuba.

Nihon yakurigaku zasshi. Folia pharmacologica Japonica
|April 30, 2025
PubMed
概括

突肉瘤是由特定的基因融合 (SS18-SSX) 引起的,它破坏了染色质重塑. 这种异常复合体劫持了基因调节,推动了癌症的发展,并提供了新的药物设计目标.

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