致命的真菌菌菌病,被误诊为接触性皮肤炎
Ghazal Shadmani1, Justin Dumrongkulraksa1, Amin Haghighat Jahromi2
1Department of Nuclear Medicine, School of Medicine, Mallinckrodt Institute of Radiology, Washington University in St Louis, 510 S Kings highway Blvd, Box 8223, St. Louis, MO, 63110, USA.
EJNMMI reports
|April 30, 2025
概括
肌肤淋巴瘤的真菌菌菌 (MF) 经常被误诊为湿疹,因为症状相似. 早期诊断和像FDG PET/CT这样的先进成像技术对于有效管理这种具有挑战性的疾病至关重要.
科学领域:
- 皮肤病学 皮肤病学
- 在瘤学瘤学.
- 放射学 放射学是一门学科.
背景情况:
- 菌根性菌病 (MF) 是一种罕见的皮肤T细胞淋巴瘤 (CTCL),表现不同.
- 临床重叠与炎症性皮肤病,如湿疹和牛皮复杂早期诊断.
- 延迟诊断MF可能会显著影响患者的结果.
研究的目的:
- 介绍FDG PET/CT在某种晚期真菌菌菌病的病例中的发现.
- 突出MF的诊断挑战和临床进展.
- 强调在持续性皮肤炎中考虑MF的重要性.
主要方法:
- 一个61岁男性的病例介绍,其组织学证实了MF.
- 详细描述临床进展,错误诊断和治疗史.
- 使用氧葡萄糖正子发射断层扫描/计算机断层扫描 (FDG PET/CT) 进行诊断评估.
主要成果:
- 患者出现了的皮疹,在一年内进展到涉及70%的身体表面积.
- 最初误诊为接触性皮肤炎导致MF诊断延迟了三年.
- 尽管进行了广泛的治疗,但患者的病情在诊断后迅速恶化.
结论:
- 这个案例强调了MF和炎症性皮肤病之间的诊断模仿.
- 临床医生应在耐火性或非典型性皮肤炎中保持对MF的高度怀疑指数.
- 全面的诊断工作,包括先进的成像,对于及时的MF诊断和管理至关重要.
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