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Updated: May 9, 2025

Interactions with and Membrane Permeabilization of Brain Mitochondria by Amyloid Fibrils
00:15

Interactions with and Membrane Permeabilization of Brain Mitochondria by Amyloid Fibrils

Published on: September 28, 2019

5.9K

通过固态NMR研究的Aβ1-42沿着初级核形成过程的结构融合和膜相互作用

Maurine K Kengwerere1, June M Kenyaga1, Peng Xiao2

  • 1Department of Chemistry, Binghamton University, State University of New York, Binghamton, NY, USA.

Communications chemistry
|April 30, 2025
PubMed
概括

阿尔茨海默病 (AD) 涉及破坏细胞膜的粉样ββ (Aβ) . 这项研究揭示了Aβ1-42形成较小的,与膜相互作用的寡合体,这解释了与Aβ1-40.0相比其更高的毒性.

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Visualizing Axonal Growth Cone Collapse and Early Amyloid β Effects in Cultured Mouse Neurons06:23

Visualizing Axonal Growth Cone Collapse and Early Amyloid β Effects in Cultured Mouse Neurons

Published on: October 30, 2018

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Analysis of β-Amyloid-induced Abnormalities on Fibrin Clot Structure by Spectroscopy and Scanning Electron Microscopy06:27

Analysis of β-Amyloid-induced Abnormalities on Fibrin Clot Structure by Spectroscopy and Scanning Electron Microscopy

Published on: November 30, 2018

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The membrane domains concentrate specific lipids and proteins at one place within the membrane, which helps in cell signaling, adhesion, and other critical cellular processes. These domains can differ in size, composition, function, and lifespan.
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The membrane comprises a group of distinct proteins responsible for carrying out a cell's specific function. For example, the plasma membrane of the human sperm, or a single germ cell, contains a unique set of proteins in the...
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