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Updated: May 9, 2025

A Novel Strategy Combining Array-CGH, Whole-exome Sequencing and In Utero Electroporation in Rodents to Identify Causative Genes for Brain Malformations
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遗传性上腺增生和神经精神疾病之间的因果关系 - - 孟德尔随机化研究

Yang Liu1, Xiaokun Gang1, Yuan Gao1

  • 1Department of Endocrinology and Metabolism, The First Hospital of Jilin University, Changchun, Jilin Province, China.

Endocrine
|April 30, 2025
PubMed
概括

与CYP21A2缺乏相关的先天性上腺增生 (CAH) 可能会降低阿尔茨海默病的风险,但会增加自闭症谱系障碍的风险,特别是通过上腺通路. 这突显了内分泌功能在神经精神疾病中的作用.

关键词:
缺少21-基酶的情况遗传性上腺过度增生表达方式 定量特征 locici门德尔的随机化

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