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Transgenic Plants02:50

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Recombinant DNA technology called transgenesis is often used to add a foreign gene or remove a detrimental gene from an organism. Such genetically modified organisms are called transgenic organisms.
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Plants are multicellular eukaryotes with tissue systems made of various cell types that carry out specific functions. Different tissues work together to perform a unique function and form an organ. Organs working together form organ systems. Vascular plants have two distinct organ systems: a shoot system and a root system. The shoot system consists of two portions: the vegetative (non-reproductive) parts of the plant, such as the leaves and the stems, and the reproductive parts of the plant,...
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The genome refers to all of the genetic material in an organism. It can range from a few million base pairs in microbial cells to several billion base pairs in many eukaryotic organisms. Genome assembly refers to the process of taking the DNA sequencing data and putting it all back together in a correct order to create a close representation of the original genome. This is followed by the identification of functional elements on the newly assembled genome, a process called genome annotation.
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Annotation of Plant Gene Function via Combined Genomics, Metabolomics and Informatics
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一个整合性的植物3D基因组数据库.

Qihang Yang1, Tong Wu2, Mengyang Liu1

  • 1State Key Laboratory of North China Crop Improvement and Regulation, Hebei International Research Center of Vegetable Functional Genomics, College of Horticulture, Hebei Agricultural University, Baoding 071000, China.

Plant communications
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概括

我们创建了3D-GDP,一个植物3D基因组数据库,以比较跨物种的基因组结构. 本资源有助于理解基因调节和三维基因组组织的进化保护.

关键词:
3D基因组序列的3D测序这就是Hi-C.染色体结构 染色体结构我们的数据库数据库数据库数据库.植物比较基因组学这个平台,就是平台,就是平台.

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科学领域:

  • 基因组学就是基因组学.
  • 生物信息学是一种生物信息学.
  • 植物生物学 植物生物学

背景情况:

  • 高通量测序已经进行了先进的3D基因组结构研究,揭示了真核生物中复杂的基因调节机制.
  • 分析和比较跨物种的3D基因组结构对于理解基因组进化和功能至关重要.

研究的目的:

  • 开发和展示3D-GDP,一个用于植物3D基因组分析和物种间比较的综合数据库.
  • 为探索保存的3D基因组结构及其在基因调节中的作用提供一个平台.

主要方法:

  • 编译了26个物种的公开可用的植物3D基因组序列.
  • 关于拓关联域 (TAD),循环,区块和基因注释的综合数据.
  • 开发生物信息工具,包括基因组浏览器,TAD功能预测和比较分析模块.

主要成果:

  • 3D-GDP提供了26个植物物种3D基因组结构的详细比较分析.
  • 该数据库有助于识别保存的TAD和循环结构.
  • 提供了对3D基因组组织的进化保护及其对基因调节的影响的见解.

结论:

  • 3D-GDP是植物功能基因组学和进化研究的宝贵资源.
  • 该平台可以系统地比较染色体结构,有助于发现保存的调节元素.
  • 该数据库支持对植物3D基因组架构与全基因组基因调节之间的关系的研究.