种族健康差异和多发性骨髓瘤风险:对能量平衡干预措施的影响
Amber J Normann1,2, Rebekah L Wilson1,3, Ellaney Matarese4
1Division of Population Sciences, Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.
Cancer prevention research (Philadelphia, Pa.)
|May 1, 2025
概括
本综述探讨了黑人成年人多发性骨髓瘤风险因素,突出了差异和需要量身定制的生活方式干预措施的需要. 对文化敏感的方法对于代表性不足的群体的癌症预防至关重要.
科学领域:
- 在瘤学瘤学.
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 多发性骨髓瘤风险受肥胖和久坐的生活方式的影响,已知种族/民族差异.
- 已知风险因素不成比例地影响黑人成年人,需要有针对性的研究.
研究的目的:
- 为了检查黑人成年人多发性骨髓瘤风险决定因素.
- 总结了将生活方式因素 (肥胖,不活动,饮食) 与疾病风险联系在一起的证据.
- 讨论能源平衡干预措施,包括文化定制,以减轻风险.
主要方法:
- 对多发性骨髓瘤风险因素和差异的现有文献的审查.
- 分析证据,将生活方式因素与黑人成年人的疾病风险联系起来.
- 检查健康生活方式指导方针的障碍.
主要成果:
- 在多发性骨髓瘤风险因素方面存在显著的种族/民族差异.
- 饮食和体育活动等可改变的因素有助于肥胖和风险.
- 在代表性不足的人群中,预防性生活方式干预的证据有限.
结论:
- 对于在黑人成年人中预防多发性骨髓瘤的文化定制的生活方式干预措施有着至关重要的需要.
- 研究应侧重于社区参与,初级保健教育和可访问的资源.
- 产生公平的临床试验证据对于所有人群至关重要.
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