孕期糖尿病和中风风险在美国黑人女性中
Shanshan Sheehy1, Hugo J Aparicio2, Nuo N Xu1
1Slone Epidemiology Center, Boston University, MA (S.S., N.N.X., L.R.).
Stroke
|May 1, 2025
概括
孕期糖尿病 (GDM) 病史在黑人女性中增加了41%的中风风险. 对于那些在GDM后患上2型糖尿病的人来说,风险明显高 (2.6倍).
科学领域:
- 心血管流行病学心血管流行病学
- 生殖内分泌学 生殖内分泌学
- 公共卫生 公共卫生
背景情况:
- 关于妊娠糖尿病 (GDM) 作为黑人女性脑血管疾病的危险因素的证据有限.
- 在这个人群中,关于发生中风作为终点的具体数据缺乏.
研究的目的:
- 评估黑人女性自我报告的GDM病史和中风事件之间的关联.
- 研究基于GDM病史和进展为2型糖尿病的中风风险分层.
主要方法:
- 美国进行了一项大型前性队列研究,对41,143名美国黑人妇女进行了调查.
- 从1995年到2021年,参与者对发生的中风进行了跟踪,并使用了Cox比例危险模型进行分析.
主要成果:
- 经历过GDM与中风风险增加41%有关 (多变量HR,1.41).
- 黑人女性有GDM病史和2型糖尿病的风险增加了2.6倍.
- 对于有GDM病史的女性,没有观察到增加中风风险,但没有进展到2型糖尿病.
结论:
- 在黑人女性中,GDM病史显著增加了中风发生率.
- 早期中风预防策略应考虑GDM病史,特别是黑人女性的GDM病史,特别是黑人女性的GDM病史,特别是黑人女性的GDM病史,特别是黑人女性的GDM病史,特别是黑人女性的GDM病史,特别是黑人女性的GDM病史,特别是黑人女性的GDM病史,特别是黑人女性的GDM病史,特别是黑人女性的GDM病史.
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