热点是:气候变化对患有状细胞疾病的孕妇的影响
Rachelle Chanmany Pastor1, Lisa Roberts1, Akshat Jain2
1School of Nursing, Loma Linda University, Loma Linda, California, United States.
Women's health reports (New Rochelle, N.Y.)
|May 1, 2025
概括
患有状细胞疾病 (SCD) 的孕妇面临气候变化带来的风险增加,特别是极端高温和脱水. 更多的研究对于了解和减轻这些对母亲健康的影响至关重要.
科学领域:
- 环境健康 环境健康
- 血液学 血液学 血液学
- 孕产妇和胎儿医学 孕产妇和胎儿医学
背景情况:
- 状细胞疾病 (SCD) 是美国普遍存在的遗传性血液疾病,不成比例地影响非裔美国人.
- 患有SCD的人的怀孕带来了明显更高的并发症风险,包括高达10倍的孕产妇死亡风险.
- 怀孕期间的生理变化加剧了SCD并发症,如血管封闭性发作 (VOE) 和感染,脱水是主要的触发因素.
研究的目的:
- 审查当前关于气候变化对SCD孕妇的影响的文献.
- 确定有关气候变化,极端高温和妊娠中SCD风险的交叉点的知识差距.
- 为突出进一步研究和临床指导对这一脆弱群体的需要.
主要方法:
- 在PubMed,Embase和Google Scholar中对2019年至2024年间发表的研究进行了全面的文献搜索.
- 搜索的重点是人类受试者,并检索了477项研究.
- 在选后,分析了20篇相关文章以评估证据.
主要成果:
- 目前的证据直接将气候变化影响与孕妇患SCD风险增加联系起来显著缺乏.
- 与气候变化相关的温度升高可以增加核心体温,血液高度和脱水,所有这些都是SCD并发症的风险因素.
- 现有的SCD临床指南强调预防脱水,强调管理环境暴露的重要性.
结论:
- 迫切需要进一步的研究来调查气候变化对SCD孕妇造成的具体风险.
- 临床医生必须教育这个高风险群体关于脱水和极端高温暴露的危险.
- 缓解气候变化相关风险需要积极主动地对患者进行教育,并可能采用新的临床策略.
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