糖尿病管理中患者对口服组合疗法的坚持:一个范围审查
Maryam Zarrinkamar1, Mojgan Geran1, Mohammad Geran2
1Department of Family Medicine, Diabetes Research Center Mazandaran University of Medical Sciences Sari Iran.
Health science reports
|May 1, 2025
概括
患者对2型糖尿病 (T2DM) 组合疗法的坚持是复杂的,受临床,经济和心理社会因素的影响. 提高坚持是改善糖尿病管理和患者结果的关键.
科学领域:
- 内分泌学 在内分泌学.
- 药理学 药理学是指药理学的学科.
- 公共卫生 公共卫生
背景情况:
- 2型糖尿病 (T2DM) 是一个重大的全球健康挑战,由生活方式和人口结构的变化加剧.
- 组合疗法对于T2DM管理至关重要,但患者的坚持仍然是有效治疗的关键障碍.
- 了解坚持模式对于优化治疗策略至关重要.
研究的目的:
- 进行范围审查,探索患者在2型糖尿病管理中遵守口服组合疗法.
- 识别影响遵守的因素和改善其策略.
主要方法:
- 在PubMed,Scopus和Web of Science进行了全面的文献搜索,直到2024年7月10日.
- 包括的研究集中在使用口服组合疗法的T2DM患者身上,遵循PRISMA-ScR指南.
- 数据的提取和合成确定了依从模式,影响因素和干预策略.
主要成果:
- 包括9项研究 (2004-2021年),采用各种依从性评估方法,药物持有率是最常见的.
- 坚持率不同:双重疗法 (49%-80.8%) 和固定剂量组合 (FDCs) (60.3%-98.9%).
- 关键影响因素包括血糖控制,体重管理,成本,治疗方案复杂性和人口统计.
结论:
- 患者对T2DM组合疗法的坚持是多因素的,涉及临床,经济和心理社会因素.
- 解决这些因素对于提高治疗效率和减少糖尿病负担至关重要.
- 以患者为中心的方法和创新的策略对于提高患者的坚持和患者的生活质量至关重要.
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