选择性,紧急和紧急心脏手术后心脏切除术外体膜氧化:来自PELS观察研究的见解
Silvia Mariani1,2, Alvaro Perazzo1,3, Maria Elena De Piero1
1Maastricht University Medical Center, Cardiovascular Research Institute Maastricht, Maastricht, The Netherlands.
JTCVS open
|May 1, 2025
概括
紧急心脏手术患者需要静脉外体膜氧化 (VA ECMO) 经历更多的并发症. 然而,住院和长期存活率与可选或紧急病例相比相似.
科学领域:
- 心脏病学 心脏病学
- 心脏外科手术 心脏外科手术
- 关键护理医学 关键护理医学
背景情况:
- 手术优先影响心脏手术的结果,紧急病例的死亡率更高.
- 手术优先对心脏切除术后静脉动脉外体膜氧化 (VA ECMO) 结果的影响尚未得到充分证实.
- 这项研究调查了心脏手术后需要VA ECMO的患者的特征和结果,按手术紧急情况分层.
研究的目的:
- 为了比较心脏手术需要VA ECMO的患者的特征,并发症和生存率.
- 为了确定是否需要心脏切除术后的紧急手术,VA ECMO与紧急或选择性手术相比,与更糟糕的结果有关.
- 分析外科优先对VA ECMO启动后住院和长期生存的影响.
主要方法:
- 成年患者需要心脏切除术后VA ECMO (2000-2020) 的回顾性多中心观察性研究.
- 在紧急,紧急和可选手术组中比较术前,手术特征,并发症和生存率.
- 混合Cox比例危险模型用于评估紧急手术和住院生存之间的关联.
主要成果:
- 该队列包括1063个可选 (52.2%),445个紧急 (21.8%) 和528个紧急 (26%) 操作.
- 紧急手术与更多的冠状动脉旁路移植和大动脉手术,以及手术前血液动力学不稳定性有关.
- 尽管在紧急情况下术后出血,中风和右心室衰竭的比率较高,但住院死亡率 (60.5%可选,57.8%紧急,63.4%紧急;P=.191) 和5年生存率相似.
结论:
- 大约25%的心脏切除术后VA ECMO在紧急心脏手术后使用.
- 需要VA ECMO的紧急操作与术后并发症的增加有关.
- 住院和5年生存率在紧急,紧急和选择性心脏切除术后VA ECMO病例中是相似的.
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