较低的语义语言流性在基线表明未来的主观认知衰退的下降
Frédérique Roy-Côté1,2, Isabelle Rouleau1,2,3, Émilie Delage1,4
1Centre de Recherche de l'Institut Universitaire de Gériatrie de Montréal (CRIUGM), Montréal, Canada.
Applied neuropsychology. Adult
|May 1, 2025
概括
老年人的主观认知衰退 (SCD) 可能是未来阿尔茨海默病风险的信号. 在基线时语言语义流性降低,特别是在类别流性测试中,表明认知能力下降的可能性更高.
科学领域:
- 神经科学是一个神经科学.
- 老年学是一门学科.
- 认知心理学 认知心理学
背景情况:
- 主观认知衰退 (SCD) 是老年人对认知功能的关注.
- 患有SCD的人患阿尔茨海默病 (AD) 的风险更高.
- 一些SCD个体可能在特定的认知领域表现出微妙的缺陷,尽管整体测试表现正常.
研究的目的:
- 为了研究SCD中的语义函数.
- 为了比较SCD进展者 (SCDp) 和非进展者 (SCDnp) 之间的语义性能.
- 为了确定基线上的语义流性是否预测未来的认知衰退.
主要方法:
- 来自CIMA-Q队列的数据分析.
- 根据年龄和教育,对25名SCDp和25名SCDnp参与者的匹配比较.
- 基线和两年后的神经心理评估,包括语义流性测试和MoCA分数.
- 使用独立样本t测试,ANCOVA和双因素ANOVA进行统计分析.
主要成果:
- 与SCDnp参与者相比,SCDnp参与者在类别 (语义) 流利性测试中表现明显差.
- 这种语义流的差异在随访时并不显著.
- 在其他认知领域没有观察到基线差异.
- 纵向分析显示,MoCA得分显著下降,仅限于SCDp组.
结论:
- 在患有SCD的老年人中,语言语义流性降低可能是未来认知衰退风险增加的早期指标.
- 语义流利性测试可以成为有价值的工具,用于识别患有SCD的个体,这些个体更有可能进展.
- 需要进一步的研究来探索SCD中的特定语义任务的预测价值.
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