青春期的骨成熟:评估骨发育和年龄指标
João Pinheiro1,2, Luís Ribeiro1,2,3,4, Diana Teixeira5
1School of Health, Gambelas Campus, University of Algarve, 8005-139 Faro, Portugal.
Diagnostics (Basel, Switzerland)
|May 1, 2025
概括
骨年龄 (SA) 与青少年的身体组成和人体测量比时间年龄更好地相关. 然而,其与骨矿物质含量和密度的联系需要进一步研究.
科学领域:
- 儿科内分泌学 儿科内分泌学
- 人类成长和发展 人类成长和发展
- 生物医学成像技术 生物医学成像技术
背景情况:
- 准确评估骨成熟对于监测儿童和青少年生长至关重要.
- 像Greulich & Pyle这样的传统方法可能缺乏精度.
- 骨年龄 (SA) 是生物成熟度的一个关键指标.
研究的目的:
- 评估骨年龄 (SA) 与骨矿物质含量 (BMC),骨矿物质密度 (BMD) 和男性青少年的身体组成 (BC) 的预测能力和相关性.
- 为了比较SA与这些参数的关联与时间年龄 (CA).
主要方法:
- 一项涉及115名年龄在12.1~15.8岁的男青少年的横截面研究.
- 骨年龄通过坦纳-怀特豪斯3 (TW3) 方法进行评估.
- 骨矿物质含量 (BMC),骨矿物质密度 (BMD) 和用双能X射线吸收计 (DXA) 测量的身体成分 (BC).
主要成果:
- SA与身高和体重有显著的相关性,表现优于CA.
- 此外,SA与瘦肉量 (LM) 和脂肪组织 (FT) 相比,SA与CA的相关性更强.
- SA和BMC或BMD之间的相关性很弱,并且在统计学上没有显著意义.
结论:
- 骨年龄比时间年龄更强烈地预测了青少年的人类测量和身体组成指标.
- 骨年龄与骨矿物质密度/含量之间的关系需要进一步的纵向研究.
- 未来的研究应该考虑营养因素来评估骨成熟度和骨健康.
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