深度学习方法用于预测癌症患者在化疗期间的身体和精神恶化
Joseph Finkelstein1, Aref Smiley1, Christina Echeverria2
1Department of Biomedical Informatics, The University of Utah, Salt Lake City, UT 84108, USA.
Diagnostics (Basel, Switzerland)
|May 1, 2025
概括
深度学习模型准确地预测化疗期间的身体和精神症状升级,使积极的患者护理成为可能. 将症状按3天间隔分组改善了更好的干预措施的预测准确性.
科学领域:
- 在瘤学瘤学.
- 医疗信息学 医疗信息学
- 人工智能的人工智能
背景情况:
- 预测化疗患者的症状升级对于及时干预和改善结果至关重要.
- 在化疗期间自我报告的身体和精神症状需要准确的预测.
研究的目的:
- 采用深度学习模型来预测化疗期间12种自我报告的症状的恶化.
- 为量身定制的预测模型将症状分为身体和精神组.
主要方法:
- 利用化疗患者每日自我报告的症状日志.
- 应用卷积神经网络 (CNN),长期短期记忆 (LSTM) 和门式循环单元 (GRU) 模型.
- 将症状分组为3至7天的间隔,以解决阶级失衡问题,训练80%的数据,评估20%的数据.
主要成果:
- 三天间隔显示出最佳的预测性能.
- 对于身体症状,CNN的准确率达到79.2%;对于精神症状,GRU的准确率达到77.2%.
- 模型性能随着更长的间隔而下降,尽管CNN和GRU显示相对稳定.
结论:
- 分类症状可以提高化学疗法期间对身体和精神健康的预测准确度.
- 深度学习模型显示出预测瘤护理中的症状升级的巨大潜力.
- 将预测模型集成到临床工作流程中可以促进主动的症状管理,并改善患者的护理.
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