体重不一致的单胆双胞胎和双胆双胞胎的生长轨迹:一个队列研究
Mariana Cortez Ferreira1, Inês Marques Mariano2, Andreia Marinhas3
1Neonatology Department, Maternidade Bissaya Barreto, Unidade Local de Saúde de Coimbra, Coimbra, Portugal. marianasoferreira@gmail.com.
European journal of pediatrics
|May 1, 2025
概括
双胞胎的体重不一致会影响生长,较小的双胞胎在36个月的年龄纠正后会出现追赶增长. 胆性会影响生长差异解决的时间,二胆双胞胎的差异持续时间更长.
科学领域:
- 围产和新生儿医学
- 儿科生长与发展 儿科生长与发展
- 双胞胎研究 双胞胎研究
背景情况:
- 体重不一致是已知的围产和新生儿不良结果的风险因素.
- 它对儿童生长模式的影响,特别是头周长和分辨率时间,尚不清楚.
- 以前的研究表明,在幼儿时代,体重和长度的差异持续存在.
研究的目的:
- 为了研究体重差异对双胞胎体重,长度和头周长增长的影响,在双胞胎中,年龄更正 (CA) 为36个月.
- 为了比较基于胆性 (单胆性与二胆性) 的生长模式.
主要方法:
- 对单和双双胞胎对进行了回顾性队列研究,重量差异>20%.
- 对出生时的体重,长度和头部周长,以及1,6,12,18,24和36个月的z-score进行分析.
- 单胆双胞胎和双胆双胞胎之间的生长参数的纵向比较.
主要成果:
- 较小的双胞胎表现出追赶增长,在36个月CA时达到与较大的双胞胎相似的增长参数.
- 与二双胞胎相比,单双胞胎的生长差异较早得到解决.
- 头周长z-score是长度之前正常化的,其次是体重z-score.
结论:
- 双胞胎之间的体重异常存在于整个生长期,但在36个月CA时,所有异常双胞胎的体重异常都会消失.
- 胆性在增长差距解决的时间上发挥着重要作用.
- 与单双胞胎相比,二双胞胎的生长参数差异在二双胞胎中持续时间更长.
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