人格评估清单 和功能性发作患者的性别差异
Madeleine P Smith1, Victoria M Kordovski1, Victor A Del Bene2
1Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Epilepsy & behavior : E&B
|May 1, 2025
概括
人格评估清单 (PAI) 档案中的性别差异区分功能性发作 (FS) 和发作 (ES). 患有FS的男性和女性表现出明显的PAI尺度升高,有助于差异诊断和治疗规划.
科学领域:
- 神经科学是一个神经科学.
- 心理学 心理学 心理学
- 临床诊断 临床诊断 临床诊断
背景情况:
- 以前的研究表明,人格评估库存 (PAI) 可以区分功能性发作 (FS) 和发作 (ES).
- 基于性别的PAI有效性和FS和ES之间的临床子表差异尚未得到广泛研究.
- 了解这些性别差异可以提高诊断的准确性,并为发作疾病提供量身定制的治疗策略.
研究的目的:
- 在FS和ES的成年人中调查PAI有效性和临床子表的性别差异.
- 为了确定PAI配置文件是否可以根据性别预测诊断状态 (FS与ES).
- 确定特定的PAI尺度和子尺度,这些尺度和子尺度对于区分FS和ES的诊断实用性最高.
主要方法:
- 对62名FS成年人和55名ES成年人的PAI尺度,子尺度和有效性概况的分析.
- 使用后勤回归,赔率比率 (OR),信心区间 (CI),正预测值 (PPV),负预测值 (NPV) 和接收器操作特征 (ROC) 曲线.
- 参与者通过约翰霍普金斯医院的连续视频脑电图 (cEEG) 进行诊断.
主要成果:
- 无论性别,FS和ES组之间没有发现PAI有效度尺度的显著差异.
- 与ES女性相比,FS女性在压力 (STR) 和体质投诉 (SOM) 尺度上显示出更高的升高.
- 与ES男性相比,FS男性报告的焦虑 (ANX),焦虑相关障碍 (ARD) 和非支持 (NON) 尺度较高. 转换 (SOM-C) 和生理焦虑 (ANX-P) 等特定的子尺度是显著的预测因素.
- 在组合样本中,SOM和SOM-C是FS的最佳预测指标,尽管整体分类率不超过80%.
结论:
- 与ES相比,患有FS的男性和女性表现出不同的PAI配置文件,特别是在转化症状方面.
- 这些特定于性别的PAI特征可能会影响FS倾向或症状延续.
- 识别这些差异可以指导开发更有效的,个性化的治疗方法FS和ES.
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