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在COPD中,CH25H/25-HC通过AMPK/STAT6通路依赖的M2巨细胞极化促进肺纤维化

Ying Li1, Guangzhi Xiao1, Xianghui Fu1

  • 1Department of Clinical Immunology, Xijing Hospital, Fourth Military Medical University, Xi'an, China.

Immunobiology
|May 1, 2025
PubMed
概括

CH25H/25-胆固醇 (25-HC) 在慢性阻塞性肺病 (COPD) 中通过激活AMPK/STAT6依赖的M2巨细胞两极分化来促进肺纤维化. 向CH25H为COPD相关纤维化提供了一个潜在的治疗策略.

关键词:
在 AMPK/STAT6 中.在CH25H/25-HC中.慢性阻塞性肺病 慢性阻塞性肺病M2 大细胞肺纤维化 肺纤维化

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