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手部尤文肉瘤:一个罕见的病例报告,包括诊断和管理方面的考虑
Sheikh Sarfraz Ali1, Mohd Fahud Khurram1, Nimisha Singh1
1Department of Plastic and Reconstructive Surgery, Jawaharlal Nehru Medical College, Aligarh Muslim University, Aligarh, Uttar Pradesh 202001, India.
International journal of surgery case reports
|May 1, 2025
概括
手部尤文肉瘤是一种罕见的疾病,可以模仿良性瘤. 早期怀疑和涉及手术和化疗的多学科方法对于这种罕见的手癌的良好结果至关重要.
科学领域:
- 整形瘤学 整形瘤学
- 儿科瘤学 儿科瘤学
- 骨辐射学 骨辐射学
背景情况:
- 尤文肉瘤 (ES) 是一种罕见的恶性瘤,主要影响青少年,通常涉及轴和尾骨.
- 手动参与非常罕见,占所有ES病例的不到1%.
- 无特异性症状和与其他疾病相似的症状往往会推迟早期诊断.
研究的目的:
- 为了突出一个罕见的Ewing肉瘤在手中的病例.
- 强调诊断的挑战和早期怀疑的重要性.
- 讨论管理和有利的预后与及时干预.
主要方法:
- 一名20岁的男性出现了6个月的指胀和不适的病史.
- 诊断工作包括体检,放射和MRI.
- 进行了手术截肢,随后进行了组织病理学确认和辅助化疗.
主要成果:
- 组织病理学证实了尤文肉瘤,其特征是单形小圆细胞和CD99阳性.
- 患者接受了包括Vincristine,Ifosfamide,Doxorubicin,Etoposide和Actinomycin-D在内的化疗方案.
- 一年后的随访没有显示出复发或转移的证据.
结论:
- 由于手部尤文肉瘤的罕见性和软组织的参与,它带来了挑战.
- 早期怀疑非典型的手部胀以及多学科的方法至关重要.
- 及时诊断,手术干预和化疗导致有利的结果,局部疾病的存活率为70-80%.
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