第二季度缺铁对母亲和婴儿的结果的影响:丹麦队列研究
Celina Pforr Ibsen1, Cathrine Scavenius1, Katrine Dige Frederiksen1
1Department of Gynecology and Obstetrics, Copenhagen University Hospital - Nordsjællands Hospital, Hillerød, Denmark.
概括
铁缺乏症 (ID) 在孕妇中很常见,影响胎盘和婴儿的生长,但没有不良结果. 需要进一步研究ID在第二个三个月的临床相关性.
科学领域:
- 产科和妇科 产科和妇科
- 孕产妇和胎儿医学 孕产妇和胎儿医学
- 营养科学 营养科学
背景情况:
- 铁在怀孕期间至关重要,但第二个三个月铁缺乏 (ID) 对母亲和婴儿健康的影响仍然不清楚.
- 了解ID的患病率和后果对于优化产前护理和结果至关重要.
研究的目的:
- 为了确定怀孕妇女在第二个三个月的ID的患病率.
- 调查第二个三个月的ID与母亲和婴儿不良结果之间的关联.
主要方法:
- 一项纵向队列研究的探索性分析,涉及单身孕妇.
- 血清费里 (P-费里) 水平在妊娠24-28周之间进行了分析.
- 使用邦费罗尼校正的多变量回归评估了ID (P-费里丁<15μg/L) 与母亲/婴儿结局之间的关联.
主要成果:
- 在449名女性中,第二季度的ID患病率为40.5%,4.4%患有贫血.
- 患有ID的女性的胎盘和婴儿出生体重较高,妊娠年龄较小的婴儿的患病率较低.
- 在第二个三个月的ID和不良结果 (如紧急剖腹产,早产或胎儿酸) 之间没有发现显著的关联.
结论:
- 尽管补充了铁,但在怀孕的丹麦妇女中,在怀孕的第二个三个月中,ID经常发生.
- ID与胎盘和婴儿增长的加速有关,但与不良妊娠结果无关.
- 目前在第二个三个月的ID切断的临床意义需要进一步调查.
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