微卫星不稳定的癌症中驱动突变的分子演变及其对瘤进展的影响:对UCEC患者的精准医学的影响

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Kalpana Sriramadasu1, Senthilkumar Ravichandran2, Yau-Hong Li3

  • 1Institute of Biomedical Sciences, National Sun Yat-Sen University, Kaohsiung, 804201, Taiwan.

Computers in biology and medicine
|May 1, 2025
PubMed
概括

癌症驱动突变 (CDM) 与微卫星不稳定性 (MSI) 或不匹配修复缺陷 (MMRd) 的高突变负载不同,影响瘤进化. 瘤突变负担 (TMB) 可以帮助将子宫癌患者分类为向治疗.

关键词:
癌症驱动突变 (CDM) 是一种癌症驱动突变.遗传进化的遗传进化免疫干预是一种免疫干预.精准医学是一门精准的医学.瘤突变负担 (TMB) 是指瘤突变负担.宫内体内膜癌 (UCEC) (子宫体内膜癌)

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