Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

A MXene@GQDs hybrid fluorescent array for rapid identification and quantification of foodborne pathogens.

Mikrochimica acta·2026
Same author

Machine learning-driven graphene quantum dot fluorescence array for rapid heavy metal ions detection and identification.

Environmental research·2025
Same author

Machine learning assisted paper-based fluorescent sensor array with metal-doped multicolor carbon quantum dots for identification and inactivation of bacteria.

Talanta·2025
Same author

Research on 3D LiDAR outdoor SLAM algorithm based on LiDAR/IMU tight coupling.

Scientific reports·2025
Same author

Machine Learning-Enhanced Bacteria Detection Using a Fluorescent Sensor Array with Functionalized Graphene Quantum Dots.

ACS applied materials & interfaces·2025
Same author

Machine learning-driven fluorescent sensor array using aqueous CsPbBr<sub>3</sub> perovskite quantum dots for rapid detection and sterilization of foodborne pathogens.

Journal of hazardous materials·2024
Same journal

HSF4 promotes lipid peroxidation by transcriptionally regulating ALOX15 during lens terminal differentiation.

Biochimica et biophysica acta. Molecular and cell biology of lipids·2026
Same journal

Corrigendum to "Inducible beige adipocytes improve impaired glucose metabolism in interscapular BAT-removal mice" [Biochim. Biophys. Acta Mol. Cell Biol. Lipids 1866 (2021) 158871].

Biochimica et biophysica acta. Molecular and cell biology of lipids·2026
Same journal

Caveolin-2 knockout suppresses the formation and progression of oral leukoplakia via lipid metabolism disruption.

Biochimica et biophysica acta. Molecular and cell biology of lipids·2026
Same journal

Lipid droplet isolation as a novel platform for spectroscopic investigation of cargo modifications.

Biochimica et biophysica acta. Molecular and cell biology of lipids·2026
Same journal

Maternal vitamin A deficiency programs offspring visceral hypersensitivity through RARβ-COX-2/PGE2 signaling.

Biochimica et biophysica acta. Molecular and cell biology of lipids·2026
Same journal

Inositol biosynthesis is inversely regulated by glycolytic activity.

Biochimica et biophysica acta. Molecular and cell biology of lipids·2026
查看所有相关文章

相关实验视频

Updated: May 9, 2025

Differentiation and Imaging of Brown Adipocytes from the Stromal Vascular Fraction of Interscapular Adipose Tissue from Newborn Mice
04:46

Differentiation and Imaging of Brown Adipocytes from the Stromal Vascular Fraction of Interscapular Adipose Tissue from Newborn Mice

Published on: February 3, 2023

1.2K

素作为双向ROS调节剂,提高了小鼠色脂肪细胞的色.

Zhixin Zhang1, Linli Zhao1, Jiahui Wang1

  • 1School of Food and Biological Engineering, Hefei University of Technology, Hefei, Anhui 230009, China.

Biochimica et biophysica acta. Molecular and cell biology of lipids
|May 1, 2025
PubMed
概括
此摘要是机器生成的。

素通过差异调节脂肪细胞和巨细胞中的活性氧物种 (ROS) 来增强色脂肪细胞热生成. 这种天然化合物通过Nrf2/Catalase通路促进脂肪细胞的色,抵消巨细胞介导的抑制.

关键词:
脂肪细胞脂肪细胞布朗宁是什么意思 布朗宁是什么意思卢特奥林是什么? 卢特奥林是什么?巨细胞是最重要的细胞.有反应性氧物种的反应性氧物种.

更多相关视频

Isolation and Differentiation of Stromal Vascular Cells to Beige/Brite Cells
07:22

Isolation and Differentiation of Stromal Vascular Cells to Beige/Brite Cells

Published on: March 28, 2013

38.6K
Visualization and Quantification of Brown and Beige Adipose Tissues in Mice using [18F]FDG Micro-PET/MR Imaging
08:31

Visualization and Quantification of Brown and Beige Adipose Tissues in Mice using [18F]FDG Micro-PET/MR Imaging

Published on: July 1, 2021

2.9K

相关实验视频

Last Updated: May 9, 2025

Differentiation and Imaging of Brown Adipocytes from the Stromal Vascular Fraction of Interscapular Adipose Tissue from Newborn Mice
04:46

Differentiation and Imaging of Brown Adipocytes from the Stromal Vascular Fraction of Interscapular Adipose Tissue from Newborn Mice

Published on: February 3, 2023

1.2K
Isolation and Differentiation of Stromal Vascular Cells to Beige/Brite Cells
07:22

Isolation and Differentiation of Stromal Vascular Cells to Beige/Brite Cells

Published on: March 28, 2013

38.6K
Visualization and Quantification of Brown and Beige Adipose Tissues in Mice using [18F]FDG Micro-PET/MR Imaging
08:31

Visualization and Quantification of Brown and Beige Adipose Tissues in Mice using [18F]FDG Micro-PET/MR Imaging

Published on: July 1, 2021

2.9K

科学领域:

  • 代谢和内分泌学
  • 细胞生物学 细胞生物学
  • 免疫学 免疫学 免疫学

背景情况:

  • 色脂肪细胞中的热生成依赖于反应性氧物种 (ROS).
  • 通过ROS激活母细胞可以抑制色脂肪细胞的分化和功能.
  • 作为一种天然的抗氧化剂,素可以调节脂肪细胞和巨细胞的反应.

研究的目的:

  • 为了研究黄素对白色脂肪细胞和巨细胞中ROS水平的影响.
  • 为了确定黄素如何影响巨细胞介导的脂肪细胞色的抑制.
  • 阐明黄素作用背后的分子机制.

主要方法:

  • 微分小鼠肌血管分数 (SVF) 细胞变成色脂肪细胞.
  • 用过氧化 (H2O2) 激活小鼠骨髓衍生性巨细胞 (BMMCs).
  • 评估细胞内ROS水平,基因表达和细胞功能.

主要成果:

  • 氨酸在色脂肪细胞中增加了ROS和发热基因表达,与N-乙半氨酸 (NAC) 不同.
  • 丁醇抑制了H2O2诱导的巨细胞激活和ROS生成.
  • 氨酸部分逆转了杆细胞诱导的色脂肪细胞分化和热生成的抑制.
  • 素的作用是由Nrf2/Catalase通路介导的.

结论:

  • 氨酸在色脂肪细胞和巨细胞中差异调节ROS.
  • 丁醇通过增强热生成和抑制巨细胞驱动的抑制来促进脂肪细胞棕色化.
  • Nrf2/Catalase通路是黄素双重作用的关键调解者.