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尼费林通过破坏p65核转位来抑制PRRSV感染

Qinqin Sun1, Yun Cheng2, Yunfei Huang2

  • 1School of Animal Science and Technology, Foshan University, Foshan, PR China; Foshan University Veterinary Teaching Hospital, Foshan University, Foshan, PR China.

Microbial pathogenesis
|May 1, 2025
PubMed
概括

尼费林是一种天然化合物,通过抑制炎症反应,有效地抑制猪生殖和呼吸系统综合征病毒 (PRRSV) 复制. 这一发现为猪中PRRSV感染提供了有前途的新疗法.

关键词:
抗病毒药物是一种抗病毒药.在 NF-κBB 中.尼弗林尼弗林尼弗林尼弗林尼尼弗林尼PRRSVV 在这个问题上.

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Protein synthesis is indispensable for viral replication, as viruses lack the cellular machinery required for this process and must hijack the host's translational apparatus. In response, host cells deploy a critical innate immune defense involving interferons, specialized cytokines that play a central role in inhibiting viral propagation.Upon viral detection, infected cells release interferons that bind to receptors on adjacent uninfected cells, activating the JAK-STAT signaling pathway and...
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