在左侧膜干预后,三管吐进展的发生率,预测因素和结果
Cheng Wang1,2, Nadira Hamid2,3, Vinayak Bapat2,3
1Center for Structural Heart Disease, Fuwai Hospital, CAMS and PUMC, Beijing, China.
Heart (British Cardiac Society)
|May 1, 2025
概括
在左侧膜心脏病 (VHD) 治疗后,三回 (TR) 进展很常见,增加死亡风险. 根据身体表面积调整三环直径 (TAD) 改善了风险评估,建议对高风险患者进行更早的干预.
科学领域:
- 心脏病学 心脏病学
- 心声回声扫描 (Echocardiography) 是一种心声回声扫描.
- 膜心脏疾病 膜心脏疾病
背景情况:
- 在左侧膜性心脏病 (VHD) 纠正后,三回 (TR) 的进展是一个重要的临床问题.
- 了解TR进展对于管理VHD治疗后的患者至关重要.
研究的目的:
- 为了确定发生率,预测因素和TR进展的结果,在接受治疗的患者大动脉或关节疾病.
- 确定与TR进展相关的因素及其对患者死亡率的影响.
主要方法:
- 对1644名没有严重TR的患者进行分析,这些患者接受了为大动脉或心脏中关节疾病进行手术或透导管治疗 (2014-2018).
- TR进展定义为在随访心声学上增加到中度或重度的TR.
- 评估基线因素,包括三环形直径 (TAD),以及它们与TR进展和结果的关联.
主要成果:
- 在5年后,TR进展发生在12.0%的患者中.
- 预测因素包括年龄较大,女性性别,心房动,心脏起器植入和较大的TAD.
- TR进展与增加全因死亡率和死亡或心力衰竭住院住院的复合相关.
结论:
- 在左侧VHD纠正后,TR进展是常见的并发症,与不良结果相关.
- 将TAD与身体表面积进行索引有助于减轻风险评估中的性别差异.
- 这些发现支持在高风险人群中考虑预防性三干预的较低门.
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