通过对人体体感官皮层进行定制的皮质内微刺激来传达触觉对象的特征
Ceci Verbaarschot1,2,3, Vahagn Karapetyan1,4, Charles M Greenspon5
1Rehab Neural Engineering Labs, University of Pittsburgh, Pittsburgh, PA, USA.
Nature communications
|May 1, 2025
概括
研究人员为四肢患者开发了一种新方法来控制感官皮层刺激,恢复虚拟对象的触觉感觉. 这种方法允许更自然的触觉感知和更好地评估人工感觉.
科学领域:
- 神经科学是一个神经科学.
- 生物医学工程 生物医学工程
- 康复医学 康复医学 康复医学
背景情况:
- 对体感皮层的微刺激可以恢复脊髓损伤患者的触觉感知.
- 目前的局限性包括探索刺激参数和评估唤起的感觉质量的挑战.
- 开发自然主义的触觉恢复方法对于改善生活质量至关重要.
研究的目的:
- 解决探索刺激参数和评估体感皮质微刺激中的感知质量的局限性.
- 为了使四肢的个体能够控制刺激参数,以创造特定对象的触觉感觉.
- 研究人工唤起的触觉感觉的特征和感知能力.
主要方法:
- 对三名四肢的男性参与者开发了一种实验范式.
- 参与者以盲目的方式控制刺激参数,以对虚拟对象产生感觉.
- 使用线性分类器和参与者匹配来评估识别刺激配置文件的能力.
主要成果:
- 参与者可靠地创造了特定对象的触觉感觉,具有生动,对象适当的特征.
- 参与者和线性分类器都能将刺激资料与在没有视觉线索的情况下显著超出机会的物体相匹配.
- 感觉之间的混增加与相关对象的触觉特征更大的相似性相关.
结论:
- 身体感官皮层微刺激可以唤起直观的触觉感知,具有不同的特性,即使没有视觉输入.
- 一种自我引导的刺激方法有效地描述了感知,并可能指导未来的刺激范式.
- 这种方法提升了恢复脊髓损伤患者复杂,自然的触觉的潜力.
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