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Updated: May 6, 2026

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在人眼透镜蛋白质组中对异构的深度表征,通过结晶体-消耗数据-独立获取

Evan E Hubbard1, Thomas A Shoff1, Manhoi Hur2,3

  • 1Department of Chemistry, University of California, California, USA.

Aging cell
|May 2, 2025
PubMed
概括

眼镜蛋白经历自发的异体化,这种改变会影响结构和疾病. 这项研究在非晶体蛋白中确定了数百个新的同位素位点,提高了年龄预测的准确性.

关键词:
数据独立获取数据独立获取眼镜眼镜眼镜眼镜眼镜眼镜人类的衰老 人类的衰老异构化的异构化蛋白质组学 蛋白质组学

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Transmission electron microscopy (TEM) can be used to determine the 3D structure of biological samples with the help of techniques such as electron microscope tomography and single-particle reconstruction. While single-particle reconstruction can examine macromolecules and macromolecular complexes in vitro conditions only, tomography permits the study of cell components or small cells in vivo.
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