调查扩大甲获取政策与阿片类药物治疗计划保留的异质效应:罗德岛基于人口的回顾性队列研究
Bennett Allen1, Noa Krawczyk1, Cale Basaraba1
1Center for Opioid Epidemiology and Policy, Department of Population Health, Grossman School of Medicine, New York University.
American journal of epidemiology
|May 2, 2025
概括
罗德岛州 罗德岛州 罗德岛州
科学领域:
- 成 药物 药物 药物 药物
- 公共卫生政策 公共卫生政策
- 阿片类药物使用障碍治疗治疗
背景情况:
- 在COVID-19大流行期间,联邦监管变化允许扩大甲获取.
- 罗德岛在2020年3月实施了政策变化,允许带回家的甲剂量.
- 长期以来对甲的限制与这项新政策形成了对比.
研究的目的:
- 为了比较六个月的患者保留在阿片类药物治疗计划 (OTPs) 在政策变化之前和之后.
- 评估扩大甲获取对治疗延续的影响.
- 确定受益于政策或受政策负面影响的患者子组.
主要方法:
- 对1248名接受OTP治疗的患者进行了回顾性队列研究.
- 从患者级OTP入院和出院记录中收集的数据.
- 后勤回归和异质治疗效应 (HTE) 扫描用于分析保留和子组异质性.
主要成果:
- 总的来说,在政策实施后,没有观察到六个月保留时间的显著变化 (aOR=1.08,aRR=1.03).
- HTE-Scan确定了两个显着增加保留率的子组:具有较低教育/逮捕历史的患者和具有逮捕历史的特定人口/物质使用配置文件.
- 没有一个子组显示显著下降的保留.
结论:
- 罗德岛州扩大甲获取并没有对整体患者保留产生负面影响.
- 该政策可能特别有利于脆弱的患者子组,包括那些受教育程度较低或特定的人口和物质使用情况的患者.
- 研究结果表明,宽松的甲法规可以支持风险人群参与阿片类药物治疗.
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