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Updated: Aug 11, 2026

Solid Phase Synthesis of a Functionalized Bis-Peptide Using "Safety Catch" Methodology
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一种快速的手动固体相合成方法,用于高通量生产

Clyde Overby1,2, Brittany Abraham1,2, Emmanuella Adjei-Sowah1,2

  • 1Department of Biomedical Engineering, University of Rochester, Rochester, New York, USA.

Journal of biomedical materials research. Part A
|May 2, 2025
PubMed
概括

一种新的快速手动固体相合成 (SPPS) 方法可以同时合多种氨基酸,比传统技术更快地产生高纯度. 这加速了用于生物医学应用的的设计和开发.

关键词:
生物材料的功能化功能化高通量的生产生产.手动合成的合成方法基于的生物材料.固相合成固相合成

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Fast Reactions01:27

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Fast reactions occurring in times shorter than the time needed to mix reactants pose a unique challenge for investigation. In a liquid-phase continuous-flow system, reactants A and B are swiftly pushed into the mixing chamber, where mixing occurs within 1 ms. The reaction mixture then flows through an observation tube, and one measures light absorption to determine species concentrations at various points of the tube. This method is most appropriate when relatively large volumes of reactants...