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在医学中,in silico试验和数字双胞胎的未来

¹Department of Radiology and Center for Virtual Imaging Trials, Duke University, 2424 Erwin Road, Durham, NC 27710, USA.

|May 2, 2025

概括

在 silico 试验和数字双胞胎通过为每个人创建一个数字双胞胎来提供个性化的医疗保健. 这种方法旨在优化医疗创新和患者护理,以实现更高效的未来.

科学领域:

生物医学工程生物医学工程
计算生物学计算生物学
医疗信息学医疗信息学

背景情况:

在 silico 试验和数字双胞胎正在成为变革性的医疗技术.
这些技术为设计,优化和评估医疗创新及其应用提供了新的方法.
它们的实用性涵盖了个性化医学和人口级别的医疗保健,可能补充或取代传统的临床试验.

研究的目的:

为推进in silico试验和数字双胞胎技术提出一个有凝聚力的月球目标.
将这一目标定义为为每个人创建个人拥有的,逐步更新的数字双胞胎.
概述这样的愿景在优化医疗保健,评估技术和产生现实世界的证据方面的潜力.

主要方法:

利用计算建模方面的进步.
整合监管科学的进展.
利用数字医疗保健基础设施的发展.

主要成果:

在 silico 试验和数字双胞胎提供有效的方式来资格,量化和个性化医疗保健创新.
这些技术可以在临床应用之前或与临床应用一起应用.
采用统一的方法可以加速实现他们的全部潜力.

结论:

为每个人都创造一个数字双胞胎的统一目标是可行的,并建立在现有工作的基础上.
实现这一愿景需要利益相关者的参与和多样化的专业知识.
这一举措可以改变医学,使其更准确,更有效,更定量.

关键词:

临床试验是指临床试验中的临床试验.数字双胞胎是一个数字双胞胎.在 silico 试验中.原型设计原型设计.康复性医学是一种康复性医学.监管科学是一种监管科学.这将彻底改变医学.虚拟临床试验是虚拟的临床试验.

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