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Updated: May 9, 2025

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准PCNA/PARP1轴可以抑制肝细胞癌的恶性进展

Jipin Li1,2, Tao Yong1,2, Yali Chen2

  • 1Department of General Surgery, The Second Hospital of Lanzhou University, Lanzhou, China.

Frontiers in pharmacology
|May 2, 2025
PubMed
概括

向增殖细胞核抗原 (PCNA) 和多 (ADP-ribose) 聚合酶1 (PARP1) 抑制了肝细胞癌 (HCC) 的生长. 抑制PCNA增强了Olaparib的敏感性,为HCC提供了一个新的治疗策略.

关键词:
修复DNA损伤的修复PARP1 的第一部分这是一个PCNA,PCNA,PCNA.细胞周期进展的细胞循环进展.肝细胞癌是肝细胞癌.

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