患有过度活动膀症状的女性患者使用和依赖二素 - 流行率和临床相关性
Artur Rogowski1, Maria Krowicka-Wasyl2, Bartosz Dybowski3
1Department of Minimally Invasive and Endoscopic Gynecology, Military Institute of Medicine, Legionowo, Poland.
Central European journal of urology
|May 2, 2025
概括
与对照组相比,女性膀过活 (OAB) 患者对GABAergic镇静催眠药的使用和依赖程度更高,如二类药物 (BDZs) 和Z药物. 然而,镇静催眠药的使用与OAB症状严重程度没有相关性.
科学领域:
- 药理学 药理学是指药理学的学科.
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 精神病学是一个精神病学.
背景情况:
- 包括二类药物 (BDZs) 和Z药物在内的GABAergic镇静催眠药被广泛使用和滥用.
- 精神病并发症越来越多地与膀过活 (OAB) 和催促性尿失禁有关.
研究的目的:
- 为了确定BDZ和/或Z药物使用在女性OAB患者中的流行率.
- 评估女性OAB患者中对BDZ和/或Z药物依赖的风险.
- 调查镇静剂-催眠药的使用与OAB症状严重程度之间的关系.
主要方法:
- 评估BDZ/Z-药物使用和依赖风险的流行率.
- 将OAB患者与来自泌尿外科诊所的非OAB对照进行比较.
- 评估了镇静剂-催眠剂使用与OAB症状严重程度之间的相关性.
主要成果:
- 与对照组相比,OAB患者在过去12个月内使用GABAergic镇静剂-催眠剂的患病率更高.
- 在OAB患者 (5.6%) 和对照组 (0.9%) 中,终身依赖诊断显著更高.
- 镇静催眠药的使用与OAB症状的严重程度没有相关性.
结论:
- 使用和依赖GABAergic镇静催眠药可能与女性患者的OAB诊断有关.
- 研究结果表明,镇静剂和催眠药的使用/依赖与尿道内科环境中的OAB之间存在潜在的联系.
- 需要进一步的研究来探索这种关系在女性泌尿和妇科患者中.
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