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Updated: May 20, 2025

Fluorescent Calcium Imaging and Subsequent In Situ Hybridization for Neuronal Precursor Characterization in Xenopus laevis
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Fluorescent Calcium Imaging and Subsequent In Situ Hybridization for Neuronal Precursor Characterization in Xenopus laevis

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使用生物物理生成模型精确推断到峰值

Gerard Joey Broussard1, Giovanni Diana2, Francisco J Urra Quiroz2

  • 1Neuroscience Institute, Washington Road, Princeton University, Princeton, New Jersey USA 08540.

Research square
|May 2, 2025
PubMed
概括

新的算法提高了神经尖端时间的准确性. 用于GCaMP指标的生物物理模型减少了假阳性,实现了准确检测行动潜力的近乎理论极限.

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相关概念视频

Feedback Regulation of Calcium Concentration01:27

Feedback Regulation of Calcium Concentration

Calcium is an essential signaling molecule required for various cellular functions. Calcium pumps and ion channels on cell and organellar membranes, such as those on the endoplasmic reticulum (ER), regulate calcium concentrations inside the cell. They remain closed, keeping the cytosolic calcium levels low at a resting state.
Various transmembrane receptors, such as G protein-coupled receptors (GPCRs), elicit a response to extracellular signals by increasing cytosolic calcium. Activated GPCRs...
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