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重新评估IgG亚类缺陷:一个追溯的比较队列研究

Damla Dogru1, Yagmur Dogru1, Faranaz Atschekzei1,2

  • 1Department of Rheumatology and Immunology, Hannover Medical School, Hannover, Germany.

Frontiers in immunology
|May 2, 2025
PubMed
概括

诊断特定的免疫球蛋白G子类缺陷 (IgGSDs) 是临床上具有意义的,因为它们与常见可变免疫缺陷 (CVID) 相比呈现出不同的症状,影响患者的护理.

关键词:
缺少IgG子类的IgG子类缺乏症.的IgG子类的IgG子类.关节炎是一种关节炎.支气管切除症是一种支气管切除症.常见的可变免疫缺陷常见的免疫缺陷.疹子 疹子 疹子主要是抗体缺乏症.

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Transcytosis of IgG01:15

Transcytosis of IgG

Transcytosis is the process in which molecules are internalized by endocytosis, transported across the cell, and released through exocytosis from the opposite end of the cell. Molecules such as insulin, immunoglobulins, and certain nutrients are transferred through the recycling endosomes by recycling and transcytosis.
IgG molecules from a mother undergo transcytosis starting around 13 weeks of gestation. The amount of IgG transferred and entering the fetal blood circulation increases with...