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从五种不同的正统牙对齐器中释放的双-A的比较评估 - - 一项采用气相色谱与质谱学相结合的体外研究

S D Milling Tania¹, S Ashwin Kumar², S Veerasankar¹

¹Department of Orthodontics, Rajas Dental College and Hospital, Kavalkinaru, Tamil Nadu, India.

Indian journal of dental research : official publication of Indian Society for Dental Research

|May 2, 2025

概括

这项研究发现,从五个牙科对齐器品牌中没有发现双甲 (BPA) 释放. 然而,检测到其他可能有毒的化合物,如二甲基甲酸盐 (DEP),需要进一步调查.

科学领域:

ортодонтика 材料科学牙科材料科学
聚合物化学聚合物化学
毒理学毒理学毒理学

背景情况:

双A (BPA) 是一种用于制造各种正牙材料的单体,包括复合材料,美学支架和热塑性对齐剂.
不完整的聚合和树脂降解可能导致BPA释放,造成潜在的健康风险.
评估来自正义牙对齐器的BPA释放对于患者安全至关重要.

研究的目的:

从五种不同的正义牙调整器中定性和定量确定双甲 (BPA) 释放.
为了评估BPA在模拟临床使用期间的不同时间间隔释放.

主要方法:

五个牙科对齐器品牌接受了模拟的口腔条件:表面磨损,浸入人工唾液和热冲击.
气相色谱被用来分析BPA的释放.
分析的时间间隔包括24小时,7天和10天.

主要成果:

双甲 (BPA) 在任何时间点都没有被检测到在任何分析的正义牙对齐器样本中.
确定了其他化学成分,在不同的时间点和对齐器类型中存在差异.

结论:

该研究得出的结论是,在研究的时间框架内,Bisphenol A (BPA) 并未从测试的正义牙科对齐器中释放出来.
检测到甲基甲酸盐 (DEP) 的存在,该化合物具有与BPA相似的潜在毒性,需要进一步调查.
建议进行进一步的研究,以了解在正牙材料中检测到的DEP等化合物的影响.

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