ACG临床指南:肝脏疾病中的营养不良和营养建议
Ashwani K Singal1, Robert J Wong2, Srinivasan Dasarathy3,4
1Department of Medicine, University of Louisville, Louisville, Kentucky, USA.
营养不良在肝病中很常见,影响患者的治疗结果. 早期评估和量身定制的营养支持,包括蛋白质摄入量和补充剂,对于治疗肝硬化和改善生存率至关重要.
科学领域:
- 肝病学 肝病学是一种肝病学.
- 临床营养学 临床营养学
- 胃肠病学 胃肠病学
背景情况:
- 营养不良,包括营养缺乏,过量或失衡,是肝病患者,特别是肝硬化患者的常见并发症.
- 它表现为微量营养素缺乏 (例如,),虚弱,并在晚期肝病中表现为肉症.
- 营养不良会对患者的结果产生负面影响,包括死亡率和肝移植成功率.
研究的目的:
- 为肝病患者评估和管理营养不良提供基于证据的指导方针.
- 为门诊患者和肝硬化住院患者概述具体的营养建议.
- 针对患有酒精相关性肝炎,代谢功能障碍相关性脂肪肝炎和肝脑病变的患者的营养策略.
主要方法:
- 使用推,评估,开发和评估 (GRADE) 系统等级的指导方针开发.
- 关于肝脏疾病中的营养不良现有文献的综述.
- 美国胃肠道学会实践参数委员会制定建议.
主要成果:
- 营养不良的患病率因评估方法和疾病严重程度而异,在晚期肝病中更高.
- 建议包括频繁的小餐,睡前小吃和咖啡对于稳定的门诊患者.
- 维生素E对于精选的与代谢功能障碍相关的脂肪肝炎患者;肠道营养对于缺乏摄入量的住院患者.
结论:
- 营养评估对于肝硬化和与酒精有关的肝炎患者至关重要,这是由于不良结果.
- 蛋白质摄入量不应受到限制,在肝脏脑病变中最好使用植物蛋白质.
- 分支链氨基酸可以提高肝脏脑病的治疗疗效.
更多相关视频
04:14Incorporation of a Survivable Liver Biopsy Procedure in Mice to Assess Non-alcoholic Steatohepatitis NASH Resolution
Published on: April 16, 2019
07:03Author Spotlight: Establishing MASLD Cell Models for Investigating Disease Mechanisms and the Lipid-Lowering Effects of Koumiss
Published on: July 19, 2024
相关概念视频
Esophageal Varices-II: Clinical Features and Management
In the initial assessment, a thorough review of the patient's medical history is vital to identify risk factors such as liver disease, alcohol...
Diseases of the Liver and Gallbladder
Cirrhosis is characterized by the scarring of hepatic lobules in the liver, which are replaced by fibrous tissue, affecting the liver's normal functioning. NAFLD, on the other hand, is caused by an excessive build-up of fat in the liver, not...
Chronic Pancreatitis II: Collaborative Care
Assessment:
Liver Regeneration
Cells of Liver
The liver comprises four major types of cells— hepatocytes, stellate, Kupffer, and sinusoidal endothelial cells. The hepatocytes are...
Enteral Nutrition II: Nasointestinal and Gastrostomy Feeding
Nasointestinal Feeding
Nasointestinal feeding involves placing a tube...
Enteral Nutrition I: Orogastric and Nasogastric Feeding
Orogastric (OG) and nasogastric (NG) feeding are two standard methods used for enteral nutrition. Enteral nutrition is often preferred over...
