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日本ERCP和ERCP后胰腺炎的现状和趋势:全国性的观察性研究
Tomoo Manaka1, Tetsuya Takikawa2, Kunio Tarasawa3
1Division of Gastroenterology, Tohoku University Graduate School of Medicine, 1-1 Seiryo-machi, Aoba-ku, Sendai, 980-8574, Japan.
Journal of gastroenterology
|May 2, 2025
概括
内镜逆行胆血管瘤学 (ERCP) 增加,但ERCP后胰腺炎 (PEP) 减少. 肠道NSAID似乎可以降低严重的PEP风险,这表明该常见程序的管理策略得到了改进.
科学领域:
- 胃肠病学 胃肠病学
- 医疗技术 医疗技术 医学技术
- 公共卫生 公共卫生
背景情况:
- 在胆道/胰腺疾病中,内镜逆行胆道细胞造影 (ERCP) 是至关重要的.
- 经ERCP后的胰腺炎 (PEP) 的风险很大,ERCP后的胰腺炎 (PEP) 的风险很大.
- 了解日本的ERCP和PEP趋势对于优化患者护理至关重要.
研究的目的:
- 分析日本ERCP程序的现状和时间趋势.
- 调查ERCP后胰腺炎 (PEP) 和严重PEP的发病率和趋势.
- 评估预防措施的有效性,包括NSAID和蛋白酶抑制剂.
主要方法:
- 使用诊断程序组合数据库 (2016-2023) 进行回顾性,基于人口的队列研究.
- 对ERCP,PEP,NSAID和蛋白酶抑制剂的趋势分析.
- 评估与PEP和严重PEP发展相关的因素.
主要成果:
- 分析了超过100万个ERCP病例; PEP发病率从9.1%降至6.4%.
- 严重的PEP发病率从0.5%降至0.33%.
- 门NSAID使用增加,并与严重PEP风险降低有关.
结论:
- ERCP的数量和治疗程序正在增加,而PEP率正在下降.
- 直肠NSAID在预防PEP进展到严重疾病方面表现有前途.
- 这些发现表明,不断发展的战略正在改善ERCP的结果.
关键词:
诊断程序的组合诊断程序的组合内镜逆行性胆血管造机图 (cholangiopancreatography) 是一种内镜逆行式胆血管造机图.非类固醇抗炎药物 非类固醇抗炎药物在ERCP后的胰腺炎.蛋白酶抑制剂是一种蛋白酶抑制剂.更多相关视频
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